(Q31142518)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754520%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library (English)

1 reference

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3 November 2019

1 reference

2

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3 November 2019

Annemarie Honegger

3

1 reference

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3 November 2019

Andreas Plückthun

7

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3 November 2019

author name string

Sandro Cesaro-Tadic

1

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3 November 2019

James H Rickard

4

1 reference

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3 November 2019

Lynda J Partridge

5

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3 November 2019

G Michael Blackburn

6

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3 November 2019

publication date

18 May 2003

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3 November 2019

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3 November 2019

volume

21

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3 November 2019

issue

6

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3 November 2019

page(s)

679-685

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Directed evolution of single proteins, metabolic pathways, and viruses

3 November 2019

cites work

1 reference

7 January 2021

Directed enzyme evolution

1 reference

7 January 2021

Man-made enzymes--from design to in vitro compartmentalisation

1 reference

7 January 2021

Molecular modeling and biocatalysis: explanations, predictions, limitations, and opportunities

1 reference

7 January 2021

Critical analysis of antibody catalysis.

1 reference

7 January 2021

Catalytic antibodies: structure and function

1 reference

7 January 2021

Reactive immunization

1 reference

7 January 2021

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

1 reference

7 January 2021

Making chemistry selectable by linking it to infectivity

1 reference

7 January 2021

In vitro selection for catalytic activity with ribosome display

1 reference

7 January 2021

Chemical selection for catalysis in combinatorial antibody libraries

1 reference

7 January 2021

Phage display of enzymes and in vitro selection for catalytic activity.

1 reference

7 January 2021

Reconstructing Aldolase Antibodies to Alter Their Substrate Specificity and Turnover

1 reference

7 January 2021

In vitro selection of enzymatically active lipase variants from phage libraries using a mechanism-based inhibitor.

1 reference

7 January 2021

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

1 reference

7 January 2021

High-throughput generation and engineering of recombinant human antibodies

1 reference

7 January 2021

Direct screening for phosphatase activity by turnover-based capture of protein catalysts

1 reference

7 January 2021

4-(Fluoromethyl)phenyl Phosphate Acts as a Mechanism-based Inhibitor of Calcineurin

1 reference

7 January 2021

Toward antibody-catalyzed hydrolysis of organophosphorus poisons

1 reference

7 January 2021

A bait and switch hapten strategy generates catalytic antibodies for phosphodiester hydrolysis

1 reference

7 January 2021

1 reference

7 January 2021

A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis.

1 reference

7 January 2021

Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102

1 reference

7 January 2021

Structure and mechanism of alkaline phosphatase

1 reference

7 January 2021

Enzyme catalysis: removing chemically 'essential' residues by site-directed mutagenesis.

1 reference

7 January 2021

Antibody-antigen complexes

1 reference

7 January 2021

An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues

1 reference

7 January 2021

When blind is better: protein design by evolution

1 reference

7 January 2021

Directed evolution to produce an alkalophilic variant from a Neocallimastix patriciarum xylanase

1 reference

7 January 2021

Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria

1 reference

7 January 2021

Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues

1 reference

7 January 2021

Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies

1 reference

7 January 2021

In vitro abzyme evolution to optimize antibody recognition for catalysis.

1 reference

7 January 2021

Novel frameworks as a source of high-affinity ligands

1 reference

7 January 2021

Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways

1 reference

7 January 2021

Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display

1 reference

7 January 2021

Alkaline phosphatase revisited: hydrolysis of alkyl phosphates

1 reference

7 January 2021

Yet Another Numbering Scheme for Immunoglobulin Variable Domains: An Automatic Modeling and Analysis Tool

1 reference

7 January 2021

Identifiers

DOI

10.1038/NBT828

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754520%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 November 2019

1053554336

0 references

1 reference