(Q31144439)

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The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo

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scholarly article

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Europe PubMed Central

29 June 2017

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo (English)

1 reference

Europe PubMed Central

29 June 2017

Alzheimer's disease

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6

object named as

Gerd Multhaup

1 reference

Europe PubMed Central

29 June 2017

Colin L. Masters

5

object named as

Colin L Masters

1 reference

Europe PubMed Central

29 June 2017

author name string

Roberto Cappai

1

1 reference

Europe PubMed Central

29 June 2017

Fang Cheng

2

1 reference

Europe PubMed Central

29 June 2017

Giuseppe D Ciccotosto

3

1 reference

Europe PubMed Central

29 June 2017

B Elise Needham

4

1 reference

Europe PubMed Central

29 June 2017

Lars-Ake Fransson

7

1 reference

Europe PubMed Central

29 June 2017

Katrin Mani

8

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Europe PubMed Central

29 June 2017

language of work or name

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publication date

27 January 2005

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Europe PubMed Central

29 June 2017

Journal of Biological Chemistry

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Europe PubMed Central

29 June 2017

280

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Europe PubMed Central

29 June 2017

14

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Europe PubMed Central

29 June 2017

13913-13920

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Europe PubMed Central

29 June 2017

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

The beta A4 amyloid precursor protein binding to copper.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Novel aspects of glypican glycobiology.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Copper-dependent autocleavage of glypican-1 heparan sulfate by nitric oxide derived from intrinsic nitrosothiols

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Prion, amyloid beta-derived Cu(II) ions, or free Zn(II) ions support S-nitroso-dependent autocleavage of glypican-1 heparan sulfate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Involvement of glycosylphosphatidylinositol-linked ceruloplasmin in the copper/zinc-nitric oxide-dependent degradation of glypican-1 heparan sulfate in rat C6 glioma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Glypican-1 as an Abeta binding HSPG in the human brain: its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Internalization of exogenously added memapsin 2 (beta-secretase) ectodomain by cells is mediated by amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Aortic wall damage in mice unable to synthesize ascorbic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409179200

21 January 2018

Identifiers

10.1074/JBC.M409179200

1 reference

Europe PubMed Central

29 June 2017

1 reference

Europe PubMed Central

29 June 2017

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