(Q31454902)

2 July 2017

Formation of the covalent chymotrypsin.antichymotrypsin complex involves no large-scale movement of the enzyme (English)

1 reference

2 July 2017

O'Malley KM

1

1 reference

PubMed ID

11027695

2 July 2017

Cooperman BS

series ordinal

2

1 reference

PubMed ID

11027695

2 July 2017

language of work or name

English

0 references

publication date

10 October 2000

1 reference

Journal of Biological Chemistry

2 July 2017

1 reference

2 July 2017

276

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2 July 2017

9

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2 July 2017

6631-6639

1 reference

On the size of the active site in proteases. I. Papain

2 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Role of the catalytic serine in the interactions of serine proteinases with protein inhibitors of the serpin family. Contribution of a covalent interaction to the binding energy of serpin-proteinase complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen bonding at the active site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Structural basis for serpin inhibitor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Inactive conformation of the serpin alpha(1)-antichymotrypsin indicates two-stage insertion of the reactive loop: implications for inhibitory function and conformational disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Determination of the operational molarity of solutions of bovine α-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Transient state kinetics tutorial using the kinetics simulation program, KINSIM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Resonance energy transfer between the active sites of myocardial-type creatine kinase (isozyme MB).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Detection and accumulation of tetrahedral intermediates in elastase catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Cryoenzymology of chymotrypsin: the detection of intermediates in the catalysis of a specific anilide substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Application of linear free energy relationships to the serpin-proteinase inhibition mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Structural basis of latency in plasminogen activator inhibitor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Biological implications of a 3 A structure of dimeric antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Major proteinase movement upon stable serpin-proteinase complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Antichymotrypsin interaction with chymotrypsin. Reactions following encounter complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Distortion of the active site of chymotrypsin complexed with a serpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

The structure of a serpin-protease complex revealed by intramolecular distance measurements using donor-donor energy migration and mapping of interaction sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Importance of the hinge region between alpha-helix F and the main part of serpins, based upon identification of the epitope of plasminogen activator inhibitor type 1 neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Topology of the stable serpin-protease complexes revealed by an autoantibody that fails to react with the monomeric conformers of antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

The kinetic mechanism of serpin-proteinase complex formation. An intermediate between the michaelis complex and the inhibited complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Antichymotrypsin interaction with chymotrypsin. Intermediates on the way to inhibited complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Isolation of the B and C chains from S-sulfonated alpha-chymotrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Protein estimation by the product of integrated peak area and flow rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Intramolecular transfer of excitation from tryptophan to 1-dimethylaminonaphthalene 5-sulfonamide in a series of model compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Modeling the uncleaved serpin antichymotrypsin and its chymotrypsin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Serpin-serine protease binding kinetics: alpha 2-antiplasmin as a model inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

Evidence that translocation of the proteinase precedes its acylation in the serpin inhibition pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008478200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008478200

1 reference

2 July 2017

1 reference

PubMed ID

11027695