(Q31913887)

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DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine

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Europe PubMed Central

PubMed publication ID

5 July 2017

DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

author name string

A J Fretland

1

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

U S Devanaboyina

2

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

N A Nangju

3

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

M A Leff

4

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

G H Xiao

5

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

S J Webb

6

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

M A Doll

7

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

D W Hein

8

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Europe PubMed Central

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5 July 2017

publication date

1 January 2001

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Europe PubMed Central

PubMed publication ID

5 July 2017

Journal of Biochemical and Molecular Toxicology

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Europe PubMed Central

PubMed publication ID

5 July 2017

15

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Europe PubMed Central

PubMed publication ID

5 July 2017

1

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Europe PubMed Central

PubMed publication ID

5 July 2017

26-33

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research

1 reference

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21 January 2018

Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats.

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21 January 2018

Mammary gland carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Sprague-Dawley rats on high- and low-fat diets.

1 reference

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21 January 2018

Activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) to mutagenic metabolites.

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21 January 2018

Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.

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21 January 2018

Possible mechanisms for PhIP-DNA adduct formation in the mammary gland of female Sprague-Dawley rats

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21 January 2018

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

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21 January 2018

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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21 January 2018

Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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21 January 2018

Preferential induction of guanine deletion at 5'-GGGA-3' in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridine.

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21 January 2018

Genomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

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21 January 2018

Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.

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21 January 2018

Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens

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21 January 2018

Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases.

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21 January 2018

Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters

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21 January 2018

Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus

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21 January 2018

Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype

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21 January 2018

DNA adduct levels and intestinal lesions in congenic rapid and slow acetylator syrian hamsters admi food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).

1 reference

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21 January 2018

Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3-methylimidazo[4,5-f]quinoline by dietary indole-3-carbinol in female rats.

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21 January 2018

Carcinogenicity of heterocyclic amines for the pancreatic duct epithelium in hamsters.

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21 January 2018

Effect of acetylator genotype on 3,2'-dimethyl-4-aminobiphenyl induced aberrant crypt foci in the colon of hamsters

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21 January 2018

The effect of age and exposure duration on cancer induction by a known carcinogen in rats, mice, and hamsters.

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The binding of 7,12-dimethylbenz[a]anthracene to mammary gland macromolecules in the hamster:effects of Enovid feeding or transplacental exposure to diethylstilboestrol

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Well-done meat intake and the risk of breast cancer.

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Dietary heterocyclic amines and cancer of the colon, rectum, bladder, and kidney: a population-based study.

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Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype

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21 January 2018

A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

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Induction of mammary tumors in female Sprague-Dawley rats by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and effect of dietary fat

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21 January 2018

2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk

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Identification of N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA

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21 January 2018

3,2′-Dimethyl-4-aminobiphenyl-DNA Adduct Formation in Tumor Target and Nontarget Organs of Rapid and Slow Acetylator Syrian Hamsters Congenic at theNAT2Locus

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Pancreatic DNA adducts formed in vitro and in vivo by the food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alphaC)

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Association between acetylator genotype and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) DNA adduct formation in colon and prostate of inbred Fischer 344 and Wistar Kyoto rats

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Role of sulfation and acetylation in the activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine to intermediates which bind DNA

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21 January 2018

Identifiers

10.1002/1099-0461(2001)15:1<26::AID-JBT3>3.0.CO;2-S

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

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