(Q33204213)

23 July 2017

title

Copper(II) binding to the human Doppel protein may mark its functional diversity from the prion protein (English)

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23 July 2017

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6

Sabine Van Doorslaer

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author name string

Grazia M Cereghetti

1

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23 July 2017

Alessandro Negro

2

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23 July 2017

Evi Vinck

3

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23 July 2017

Maria L Massimino

4

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23 July 2017

Maria C Sorgato

5

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23 July 2017

language of work or name

English

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publication date

24 June 2004

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Journal of Biological Chemistry

23 July 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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23 July 2017

volume

279

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23 July 2017

issue

35

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23 July 2017

page(s)

36497-36503

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Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

23 July 2017

cites work

1 reference

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Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

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Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

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Two different neurodegenerative diseases caused by proteins with similar structures

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NMR structure of the human doppel protein

21 January 2018

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Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

21 January 2018

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Doppel-induced cerebellar degeneration in transgenic mice

21 January 2018

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Absence of the prion protein homologue Doppel causes male sterility

21 January 2018

1 reference

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The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa

21 January 2018

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Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration

21 January 2018

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Prion protein selectively binds copper(II) ions

21 January 2018

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Copper binding to the prion protein: structural implications of four identical cooperative binding sites

21 January 2018

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Electron paramagnetic resonance evidence for binding of Cu(2+) to the C-terminal domain of the murine prion protein

21 January 2018

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Copper stimulates endocytosis of the prion protein

21 January 2018

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Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells

21 January 2018

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Stability and Cu(II) binding of prion protein variants related to inherited human prion diseases

21 January 2018

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Normal prion protein has an activity like that of superoxide dismutase.

21 January 2018

1 reference

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The PrP-like protein Doppel binds copper

21 January 2018

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Structural implications derived from the analysis of electron paramagnetic resonance spectra of natural and artificial copper proteins.

21 January 2018

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Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy

21 January 2018

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Copper coordination in the full-length, recombinant prion protein

21 January 2018

1 reference

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Molecular features of the copper binding sites in the octarepeat domain of the prion protein

21 January 2018

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Anterograde and retrograde intracellular trafficking of fluorescent cellular prion protein

21 January 2018

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The Metabolism and Imaging in Live Cells of the Bovine Prion Protein in Its Native Form or Carrying Single Amino Acid Substitutions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M404341200

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23 July 2017

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