(Q33232465)

24 July 2017

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title

Ribosome display for improved biotherapeutic molecules (English)

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24 July 2017

Barbara E Power

3

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author name string

Achim Rothe

series ordinal

1

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24 July 2017

Ralf J Hosse

series ordinal

2

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24 July 2017

language of work or name

English

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publication date

1 February 2006

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Expert Opinion on Biological Therapy

24 July 2017

published in

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24 July 2017

volume

6

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24 July 2017

issue

2

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24 July 2017

page(s)

177-187

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An in vitro polysome display system for identifying ligands from very large peptide libraries

24 July 2017

cites work

1 reference

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21 January 2018

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Selecting and evolving functional proteins in vitro by ribosome display

21 January 2018

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High-affinity binders selected from designed ankyrin repeat protein libraries

21 January 2018

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Ribosome display and affinity maturation: from antibodies to single V-domains and steps towards cancer therapeutics

21 January 2018

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Directed evolution of high-affinity antibody mimics using mRNA display

21 January 2018

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The use of mRNA display to select high-affinity protein-binding peptides

21 January 2018

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Man-made cell-like compartments for molecular evolution

21 January 2018

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Engineered antibody fragments and the rise of single domains

21 January 2018

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Selecting and screening recombinant antibody libraries

21 January 2018

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Ribosome display: next-generation display technologies for production of antibodies in vitro

21 January 2018

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Functional selection of vaccine candidate peptides from Staphylococcus aureus whole-genome expression libraries in vitro

21 January 2018

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In vitro selection for catalytic activity with ribosome display

21 January 2018

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Ribosomal synthesis of unnatural peptides

21 January 2018

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In vitro display technologies: novel developments and applications

21 January 2018

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Recombinant antibodies for cancer diagnosis and therapy

21 January 2018

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Panning and selection of proteins using ribosome display

21 January 2018

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Ribosome display: cell-free protein display technology

21 January 2018

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Modified peptide selection in vitro by introduction of a protein-RNA interaction.

21 January 2018

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A system based on specific protein-RNA interactions for analysis of target protein-protein interactions in vitro: successful selection of membrane-bound Bak-Bcl-xL proteins in vitro

21 January 2018

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Binding proteins from alternative scaffolds

21 January 2018

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In-vitro protein evolution by ribosome display and mRNA display

21 January 2018

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Searching sequence space for high-affinity binding peptides using ribosome display

21 January 2018

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Ribosome display of mammalian receptor domains

21 January 2018

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Identification of a functional epitope of the Nogo receptor by a combinatorial approach using ribosome display

21 January 2018

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Engineering novel binding proteins from nonimmunoglobulin domains

21 January 2018

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Functional proteins from a random-sequence library

21 January 2018

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In vitro selection as a powerful tool for the applied evolution of proteins and peptides.

21 January 2018

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Unnatural RNA display libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Comparison of Escherichia coli and rabbit reticulocyte ribosome display systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Selection of a human anti-progesterone antibody fragment from a transgenic mouse library by ARM ribosome display

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Selection of scFvs specific for HBV DNA polymerase using ribosome display.

21 January 2018

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Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display

21 January 2018

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Ribosome display of antibodies: expression, specificity and recovery in a eukaryotic system

21 January 2018

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Recombination of protein domains facilitated by co-translational folding in eukaryotes.

21 January 2018

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Cotranslational folding--omnia mea mecum porto?

21 January 2018

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Folding of a nascent peptide on the ribosome

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Functional antibody production using cell-free translation: effects of protein disulfide isomerase and chaperones.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.6.2.177

In vitro selection and evolution of functional proteins by using ribosome display

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

The tandem affinity purification (TAP) method: a general procedure of protein complex purification

21 January 2018

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In vitro selection of Jun-associated proteins using mRNA display

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

21 January 2018

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New genotype-phenotype linkages for directed evolution of functional proteins

21 January 2018

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Large antibody display libraries for isolation of high-affinity antibodies

21 January 2018

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Totally in vitro protein selection using mRNA-protein fusions and ribosome display

21 January 2018

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Applications of ribosome display to antibody drug discovery

21 January 2018

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Strategies for selection from protein libraries composed of de novo designed secondary structure modules.

21 January 2018

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Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting.

21 January 2018

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Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Structure-based improvement of the biophysical properties of immunoglobulin VH domains with a generalizable approach

21 January 2018

1 reference

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SDR grafting--a new approach to antibody humanization

21 January 2018

1 reference

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High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Effects of substitutions in the binding surface of an antibody on antigen affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Structural correlates of an anticarcinoma antibody: identification of specificity-determining residues (SDRs) and development of a minimally immunogenic antibody variant by retention of SDRs only

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Functional humanization of an anti-CD30 Fab fragment for the immunotherapy of Hodgkin's lymphoma using an in vitro evolution approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

A general method for greatly improving the affinity of antibodies by using combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Use of mutator cells as a means for increasing production levels of a recombinant antibody directed against Hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Identification of framework residues in a secreted recombinant antibody fragment that control production level and localization in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

A new approach for rapidly reshaping single-chain antibody in vitro by combining DNA shuffling with ribosome display

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Molecular evolution by staggered extension process (StEP) in vitro recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

In vitro display technologies - new tools for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Finishing the euchromatic sequence of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Current methods for the generation of human antibodies for the treatment of autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Selection of hapten-specific single-domain antibodies from a non-immunized llama ribosome display library

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Ribosome display for selection of active dihydrofolate reductase mutants using immobilized methotrexate on agarose beads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Altering the sequence specificity of HaeIII methyltransferase by directed evolution using in vitro compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

High-throughput cell-free systems for synthesis of functionally active proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Cell-free protein synthesis for proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Inhibition of human interleukin-13-induced respiratory and oesophageal inflammation by anti-human-interleukin-13 antibody (CAT-354).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Co-translational Folding of an Eukaryotic Multidomain Protein in a Prokaryotic Translation System

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Affinity maturation of a V(H)H by mutational hotspot randomization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

Directed evolution of protein inhibitors of DNA-nucleases by in vitro compartmentalization (IVC) and nano-droplet delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.6.2.177

21 January 2018

Identifiers

DOI

10.1517/14712598.6.2.177

1 reference

24 July 2017

1 reference