(Q33243131)

English

Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.

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scholarly article

1 reference

Europe PubMed Central

13 October 2017

Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5. (English)

1 reference

Europe PubMed Central

13 October 2017

Miles D. Houslay

12

1 reference

Europe PubMed Central

13 October 2017

author name string

Graeme B Bolger

1

1 reference

Europe PubMed Central

13 October 2017

George S Baillie

2

1 reference

Europe PubMed Central

13 October 2017

Xiang Li

3

1 reference

Europe PubMed Central

13 October 2017

Martin J Lynch

4

1 reference

Europe PubMed Central

13 October 2017

Pawel Herzyk

5

1 reference

Europe PubMed Central

13 October 2017

Ahmed Mohamed

6

1 reference

Europe PubMed Central

13 October 2017

Lisa High Mitchell

7

1 reference

Europe PubMed Central

13 October 2017

Angela McCahill

8

1 reference

Europe PubMed Central

13 October 2017

Christian Hundsrucker

9

1 reference

Europe PubMed Central

13 October 2017

Enno Klussmann

10

1 reference

Europe PubMed Central

13 October 2017

David R Adams

11

1 reference

Europe PubMed Central

13 October 2017

language of work or name

0 references

publication date

1 August 2006

1 reference

Europe PubMed Central

13 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

13 October 2017

398

1 reference

Europe PubMed Central

13 October 2017

23-36

1 reference

Europe PubMed Central

13 October 2017

1

1 reference

Europe PubMed Central

13 October 2017

Keynote review: phosphodiesterase-4 as a therapeutic target

1 reference

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RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with beta arrestin to control the protein kinase A/AKAP79-mediated switching of the beta2-adrenergic receptor to activation of ERK in HEK293B2 cells.

1 reference

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1 reference

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21 June 2018

Life after PDE4: overcoming adverse events with dual-specificity phosphodiesterase inhibitors

1 reference

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21 June 2018

Transduction of receptor signals by beta-arrestins

1 reference

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Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes

1 reference

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beta-Arrestin2, interacting with phosphodiesterase 4, regulates synaptic release probability and presynaptic inhibition by opioids

1 reference

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Phosphodiesterase 4-selective inhibition: novel therapy for the inflammation of COPD.

1 reference

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21 June 2018

Structural basis for the activity of drugs that inhibit phosphodiesterases

1 reference

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AKAP signalling complexes: focal points in space and time

1 reference

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A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases

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siRNA Selection Server: an automated siRNA oligonucleotide prediction server

1 reference

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21 June 2018

Beta-adrenergic receptors and their interacting proteins

1 reference

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21 June 2018

Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4).

1 reference

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21 June 2018

The potential of phosphodiesterase 4 inhibitors for the treatment of depression: opportunities and challenges.

1 reference

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21 June 2018

The Crystal Structure of AMP-Bound PDE4 Suggests a Mechanism for Phosphodiesterase Catalysis,

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases

1 reference

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21 June 2018

Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system

1 reference

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21 June 2018

Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

The RACK1 scaffold protein: a dynamic cog in cell response mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

21 June 2018

Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.

1 reference

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Crystal structure of phosphodiesterase 4D and inhibitor complex(1)

1 reference

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21 June 2018

Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1525009

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The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports--principles and applications

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

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21 June 2018

TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid

1 reference

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21 June 2018

Identification of a surface on the beta-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5

1 reference

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The next generation of PDE4 inhibitors

1 reference

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21 June 2018

Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area

1 reference

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Cyclic nucleotide phosphodiesterases: relating structure and function

1 reference

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1 reference

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1 reference

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The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform

1 reference

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Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

1 reference

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Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene

1 reference

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1 reference

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A conditionally expressed third partner stabilizes or prevents the formation of a transcriptional activator in a three-hybrid system

1 reference

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12 December 2020

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Identifiers

10.1042/BJ20060423

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

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