(Q40633113)

22 September 2017

The unique amino-terminal region of the PDE4D5 cAMP phosphodiesterase isoform confers preferential interaction with beta-arrestins (English)

1 reference

22 September 2017

7

1 reference

22 September 2017

Graeme B Bolger

1

1 reference

22 September 2017

Angela McCahill

2

1 reference

22 September 2017

Elaine Huston

3

1 reference

22 September 2017

York-Fong Cheung

4

1 reference

22 September 2017

Theresa McSorley

5

1 reference

22 September 2017

George S Baillie

6

1 reference

22 September 2017

language of work or name

English

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publication date

18 September 2003

1 reference

Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

49

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22 September 2017

49230-49238

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Complexity and diversity of mammalian adenylyl cyclases

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Beta-Arrestins: new roles in regulating heptahelical receptors' functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Arresting developments in heptahelical receptor signaling and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Cyclic nucleotide research -- still expanding after half a century

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

PDE4 cAMP-specific phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Recent advances in PDE4 inhibitors as immunoregulators and anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Activation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation. Identification and function of an inhibitory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Ligand regulation of green fluorescent protein-tagged forms of the human beta(1)- and beta(2)-adrenoceptors; comparisons with the unmodified receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Dancing with different partners: protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Regulation of G protein-coupled receptor signaling by scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Enhanced morphine analgesia in mice lacking beta-arrestin 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

Phosphodiesterases: the journey towards therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303772200

21 January 2018

Identifiers

DOI

10.1074/JBC.M303772200

1 reference

22 September 2017

1 reference