(Q33247896)

24 July 2017

Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis (English)

1 reference

24 July 2017

1 reference

Carly R K Loeb

1

1 reference

24 July 2017

Jennifer L Harris

series ordinal

2

1 reference

24 July 2017

Charles S Craik

series ordinal

3

1 reference

24 July 2017

language of work or name

English

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publication date

23 June 2006

1 reference

Journal of Biological Chemistry

24 July 2017

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24 July 2017

281

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24 July 2017

38

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24 July 2017

28326-28335

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Lymphocyte-mediated cytotoxicity.

24 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

A fresh look at tumor immunosurveillance and immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Definition and redesign of the extended substrate specificity of granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Epstein-Barr Virus EBNA-2 gene expression enhances lymphotoxin production by B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Intracellular delivery of proteins with a new lipid-mediated delivery system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

The role of fibroblast growth factors and their receptors in prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Role of fibroblast growth factor receptor signaling in prostate cancer cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Alternative splicing of fibroblast growth factor receptors in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Constitutive expression of FGF2/bFGF in non-tumorigenic human prostatic epithelial cells results in the acquisition of a partial neoplastic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

An invitation to T and more: notch signaling in lymphopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Epstein-Barr virus EBNA2 blocks Nur77- mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Requirement of caspase-mediated cleavage of c-Abl during stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Filamin (280-kDa Actin-binding Protein) Is a Caspase Substrate and Is Also Cleaved Directly by the Cytotoxic T Lymphocyte Protease Granzyme B during Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

A proteomic approach for the discovery of protease substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604544200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604544200

1 reference

24 July 2017

1 reference