(Q33264255)

English

Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders

scientific article

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scholarly article

1 reference

Europe PubMed Central

24 July 2017

Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders (English)

1 reference

Europe PubMed Central

24 July 2017

G protein-coupled receptor

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RNA interference

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based on heuristic

inferred from title

object named as

John F Cryan

11

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object named as

Daniel Hoyer

1

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author name string

Deepak R Thakker

2

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Europe PubMed Central

24 July 2017

François Natt

3

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Europe PubMed Central

24 July 2017

Rainer Maier

4

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Europe PubMed Central

24 July 2017

Dieter Huesken

5

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Europe PubMed Central

24 July 2017

Matthias Müller

6

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Europe PubMed Central

24 July 2017

Peter Flor

7

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Europe PubMed Central

24 July 2017

Herman VAN DER Putten

8

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Europe PubMed Central

24 July 2017

Markus Schmutz

9

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Europe PubMed Central

24 July 2017

Graeme Bilbe

10

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Europe PubMed Central

24 July 2017

publication date

1 January 2006

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Europe PubMed Central

24 July 2017

Journal of Receptors and Signal Transduction

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Europe PubMed Central

24 July 2017

26

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24 July 2017

5-6

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24 July 2017

527-547

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24 July 2017

describes a project that uses

RNA interference

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based on heuristic

inferred from title

Antisense oligonucleotides in psychopharmacology and behaviour: promises and pitfalls

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Efficient and specific down-regulation of prion protein expression by RNAi

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An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.

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Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer

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RNAi therapeutics: how likely, how soon?

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Therapeutic potential of RNA interference

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Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

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Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

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Rnai as an experimental and therapeutic tool to study and regulate physiological and disease processes.

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

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Mechanisms of gene silencing by double-stranded RNA

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Interfering with the brain: use of RNA interference for understanding the pathophysiology of psychiatric and neurological disorders

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siRNA relieves chronic neuropathic pain

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Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

1 reference

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siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

1 reference

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mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity

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Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

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In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice

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Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice

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Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter

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Spatial distribution of kainate receptor subunit mRNA in the mouse basal ganglia and ventral mesencephalon

1 reference

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Local gene knockdown in the brain using viral-mediated RNA interference.

1 reference

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Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain

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RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

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siRNA-mediated gene silencing in vitro and in vivo.

1 reference

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Molecular neurobiology of drug addiction

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Catching up on schizophrenia: natural history and neurobiology

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The neurobiology and control of anxious states

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Preclinical models: status of basic research in depression

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

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Lack of efficacy of 'naked' small interfering RNA applied directly to rat brain.

1 reference

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Attenuation of alpha2A-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood

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Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

1 reference

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1 reference

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Intrathecal neostigmine reduces the zymosan-induced inflammatory response in a mouse air pouch model via adrenomedullary activity: involvement of spinal muscarinic type 2 receptors

1 reference

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21 January 2018

Identifiers

10.1080/10799890600929663

1 reference

Europe PubMed Central

24 July 2017

1 reference

Europe PubMed Central

24 July 2017

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