(Q33268817)

24 July 2017

title

P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors (English)

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24 July 2017

Frances J Sharom

2

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author name string

Paul D W Eckford

series ordinal

1

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24 July 2017

publication date

1 December 2006

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Biochemistry and Cell Biology

24 July 2017

published in

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24 July 2017

volume

84

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24 July 2017

issue

6

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24 July 2017

page(s)

1022-1033

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ABC transporters in lipid transport

24 July 2017

cites work

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Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein

21 January 2018

1 reference

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

21 January 2018

1 reference

Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter

21 January 2018

1 reference

MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli

21 January 2018

1 reference

The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

21 January 2018

1 reference

Mechanisms of cancer drug resistance

21 January 2018

1 reference

Is the multidrug transporter a flippase?

21 January 2018

1 reference

Natural phosphatidylcholine is actively translocated across the plasma membrane to the surface of mammalian cells

21 January 2018

1 reference

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

21 January 2018

1 reference

Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

21 January 2018

1 reference

Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.

21 January 2018

1 reference

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

21 January 2018

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Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site.

21 January 2018

1 reference

Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance

21 January 2018

1 reference

A simplification of the protein assay method of Lowry et al. which is more generally applicable

21 January 2018

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Proximity of bound Hoechst 33342 to the ATPase catalytic sites places the drug binding site of P-glycoprotein within the cytoplasmic membrane leaflet

21 January 2018

1 reference

RETRACTED: Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharide

21 January 2018

1 reference

The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter.

21 January 2018

1 reference

Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

21 January 2018

1 reference

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

21 January 2018

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MDR1 causes resistance to the antitumour drug miltefosine

21 January 2018

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Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

21 January 2018

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Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

21 January 2018

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Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation

21 January 2018

1 reference

Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies

21 January 2018

1 reference

MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping

21 January 2018

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

21 January 2018

1 reference

ABC lipid transporters: extruders, flippases, or flopless activators?

21 January 2018

1 reference

Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis

21 January 2018

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Transport of (glyco)sphingolipids in and between cellular membranes; multidrug transporters and lateral domains

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/O06-196

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24 July 2017

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