(Q33284533)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17500591%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection (English)

1 reference

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30 December 2019

1 reference

1

1 reference

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30 December 2019

Antony J Cutler

2

1 reference

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30 December 2019

Stefan Magez

4

1 reference

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30 December 2019

Paul M Kaye

11

1 reference

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30 December 2019

5

Christoph Holscher

1 reference

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30 December 2019

12

Frank Brombacher

1 reference

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30 December 2019

author name string

J Claire Hoving

3

1 reference

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30 December 2019

Andreas Bohms

6

1 reference

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30 December 2019

Berenice Arendse

7

1 reference

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30 December 2019

Richard Kirsch

8

1 reference

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30 December 2019

Thomas Hunig

9

1 reference

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30 December 2019

James Alexander

10

1 reference

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30 December 2019

publication date

1 May 2007

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30 December 2019

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30 December 2019

volume

3

1 reference

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30 December 2019

issue

5

1 reference

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30 December 2019

page(s)

e68

1 reference

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Creative Commons Attribution 4.0 International

30 December 2019

copyright license

start time

11 May 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

1 reference

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Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens

21 June 2018

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A role for IgG immune complexes during infection with the intracellular pathogen Leishmania

21 June 2018

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Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.

21 June 2018

1 reference

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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

21 June 2018

1 reference

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The immunology of susceptibility and resistance to Leishmania major in mice

21 June 2018

1 reference

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Real-time PCR for detection and quantitation of leishmania in mouse tissues

21 June 2018

1 reference

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The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure.

21 June 2018

1 reference

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Interleukin-4 receptor alpha-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

IL-13 is a susceptibility factor for Leishmania major infection.

21 June 2018

1 reference

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Cure of progressive murine leishmaniasis: interleukin 4 dominance is abolished by transient CD4(+) T cell depletion and T helper cell type 1-selective cytokine therapy

21 June 2018

1 reference

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The IL-4 receptor: signaling mechanisms and biologic functions

21 June 2018

1 reference

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Impaired development of Th2 cells in IL-13-deficient mice.

21 June 2018

1 reference

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Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 June 2018

1 reference

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Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Recombinant interleukin 12 cures mice infected with Leishmania major

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Acquisition of lymphokine-producing phenotype by CD4+ T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

The regulation of immunity to Leishmania major

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

IL-4 directs the development of Th2-like helper effectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

21 June 2018

1 reference

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Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis

21 June 2018

1 reference

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Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function

21 June 2018

1 reference

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Macrophage deactivation by interleukin 10

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Changes in the precursor frequencies of IL-4 and IFN-gamma secreting CD4+ cells correlate with resolution of lesions in murine cutaneous leishmaniasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

IL-9 is a susceptibility factor in Leishmania major infection by promoting detrimental Th2/type 2 responses

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Activation requirements for the induction of CD4+CD25+ T cell suppressor function

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Interleukin-4 and interleukin-13 signaling connections maps

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

The role of IL-12 in maintaining resistance to Leishmania major.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Arginase I induction in macrophages, triggered by Th2-type cytokines, supports the growth of intracellular Leishmania parasites.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

IL-4-deficient Balb/c mice resist infection with Leishmania major

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Conditional gene targeting

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

IL-10 inhibits cytokine production, vascular leakage, and swelling during T helper 1 cell-induced delayed-type hypersensitivity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Early parasite containment is decisive for resistance to Leishmania major infection.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867380

Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

10 December 2018

1 reference

12 December 2020

The role of IL-10 in promoting disease progression in leishmaniasis

1 reference

12 December 2020

IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice

1 reference

12 December 2020

Interleukin-10 inhibits antimicrobial activity against Leishmania major in murine macrophages

1 reference

12 December 2020

Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development

1 reference

12 December 2020

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones

1 reference

12 December 2020

Susceptibility to Leishmania major infection in interleukin-4-deficient mice

1 reference

12 December 2020

Effects of IL-13 on murine listeriosis

1 reference

12 December 2020

Interleukin-13 effects on activated monocytes lead to novel cytokine secretion profiles intermediate between those induced by interleukin-10 and by interferon-gamma

1 reference

12 December 2020

Cutting edge: IL-12 induces CD4+CD25- T cell activation in the presence of T regulatory cells

1 reference

12 December 2020

Cutting edge: IL-4-induced protection of CD4+CD25- Th cells from CD4+CD25+ regulatory T cell-mediated suppression

1 reference

12 December 2020

Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection

1 reference

12 December 2020

CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice

1 reference

12 December 2020

The Relative Contribution of IL-4 Receptor Signaling and IL-10 to Susceptibility toLeishmania major

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.0030068

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17500591%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17500591%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference