(Q33294928)

25 July 2017

title

p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels (English)

1 reference

polycystic kidney disease

25 July 2017

main subject

1 reference

Jin-Young Park

1

1 reference

25 July 2017

William E Schutzer

2

1 reference

25 July 2017

Jessie N Lindsley

3

1 reference

25 July 2017

Susan P Bagby

4

1 reference

25 July 2017

Terry T Oyama

5

1 reference

25 July 2017

Sharon Anderson

6

1 reference

25 July 2017

Robert H Weiss

7

1 reference

25 July 2017

publication date

22 August 2007

1 reference

25 July 2017

1 reference

25 July 2017

volume

8

1 reference

25 July 2017

page(s)

12

1 reference

describes a project that uses

25 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2045080/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2369-8-12

0 references

cites work

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

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Caspase inhibition reduces tubular apoptosis and proliferation and slows disease progression in polycystic kidney disease

21 June 2018

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Involvement of down-regulation of Cdk2 activity in hepatocyte growth factor-induced cell cycle arrest at G1 in the human hepatocellular carcinoma cell line HepG2.

21 June 2018

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Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP.

21 June 2018

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p21Waf1/Cip1 as a therapeutic target in breast and other cancers

21 June 2018

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Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis

21 June 2018

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An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells

21 June 2018

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Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting [...]

21 June 2018

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PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

21 June 2018

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 June 2018

1 reference

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Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells

21 June 2018

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p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation

21 June 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 June 2018

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Cytoprotective effects of hematopoietic growth factors on primary human acute myeloid leukemias are not mediated through changes in BCL-2, bax, or p21WAF1/CIP1.

21 June 2018

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

21 June 2018

1 reference

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New functional activities for the p21 family of CDK inhibitors

21 June 2018

1 reference

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p21 is a universal inhibitor of cyclin kinases

21 June 2018

1 reference

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 June 2018

1 reference

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21 June 2018

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Apoptosis and loss of renal tissue in polycystic kidney diseases

21 June 2018

1 reference

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Polycystic kidney disease: neoplasia in disguise

21 June 2018

1 reference

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Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

21 June 2018

1 reference

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Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease

21 June 2018

1 reference

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Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2369-8-12

Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

21 January 2018

1 reference

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Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.

21 January 2018

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Gender hormones and the progression of experimental polycystic kidney disease.

21 January 2018

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Gender and the effect of gonadal hormones on the progression of inherited polycystic kidney disease in rats.

21 January 2018

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Exogenous attenuation of p21(Waf1/Cip1) decreases mesangial cell hypertrophy as a result of hyperglycemia and IGF-1.

21 January 2018

1 reference

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Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation

21 January 2018

1 reference

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High-dose estrogen and clinical selective estrogen receptor modulators induce growth arrest, p21, and p53 in primate ovarian surface epithelial cells

21 January 2018

1 reference

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Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors

21 January 2018

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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2369-8-12

Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

21 January 2018

1 reference

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Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2369-8-12

p21 is a prognostic marker for renal cell carcinoma: implications for novel therapeutic approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2369-8-12

The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2369-8-12

Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2369-8-12

Induction of p21WAF1 expression protects HT29 colon cancer cells from apoptosis induced by cryoinjury.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045080

31 October 2018

Identifiers

DOI

10.1186/1471-2369-8-12

1 reference

Dimensions Publication ID

25 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2369-8-12

9 September 2019

1 reference

25 July 2017

1 reference