(Q33294992)

25 July 2017

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title

Increasing the robustness and validity of RNAi screens (English)

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25 July 2017

Steven A Haney

1

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25 July 2017

publication date

1 August 2007

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25 July 2017

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25 July 2017

volume

8

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25 July 2017

issue

8

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25 July 2017

page(s)

1037-1049

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shRNA libraries and their use in cancer genetics

25 July 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

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Applications of high-throughput RNA interference screens to problems in cell and developmental biology

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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

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Synthetic lethal screen identification of chemosensitizer loci in cancer cells

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Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

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Systems biology in drug discovery

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Modelling data across labs, genomes, space and time

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A review of standards for data exchange within systems biology

21 January 2018

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Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

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Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

21 January 2018

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A protein sensor for siRNA asymmetry

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Structural domains in RNAi

21 January 2018

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Post-transcriptional gene silencing by siRNAs and miRNAs

21 January 2018

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Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

21 January 2018

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

21 January 2018

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A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens

21 January 2018

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Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

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Natural selection is not required to explain universal compositional patterns in rRNA secondary structure categories

21 January 2018

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3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

21 January 2018

1 reference

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

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A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

21 January 2018

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A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 January 2018

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Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

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Tumor inhibition by genomically integrated inducible RNAi-cassettes

21 January 2018

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A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

21 January 2018

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A genetic screen for candidate tumor suppressors identifies REST

21 January 2018

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An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

21 January 2018

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An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

21 January 2018

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Defining and assaying RNAi in mammalian cells

21 January 2018

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Repeated observation of breast tumor subtypes in independent gene expression data sets

21 January 2018

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Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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Analysis of cell-based RNAi screens.

21 January 2018

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Informatics and quantitative analysis in biological imaging

21 January 2018

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Statistical practice in high-throughput screening data analysis

21 January 2018

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Designing screens: how to make your hits a hit.

21 January 2018

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LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

21 January 2018

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High-throughput screening by RNA interference: control of two distinct types of variance

21 January 2018

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A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays

21 January 2018

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Delivery of RNA interference

21 January 2018

1 reference

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Drug-like properties and the causes of poor solubility and poor permeability

21 January 2018

1 reference

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High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs

21 January 2018

1 reference

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Single cell profiling of potentiated phospho-protein networks in cancer cells.

21 January 2018

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Multidimensional drug profiling by automated microscopy.

21 January 2018

1 reference

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Linking data to models: data regression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

Compound classification using image-based cellular phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

Evaluation of gene expression measurements from commercial microarray platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

Reliability and reproducibility issues in DNA microarray measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

Independence and reproducibility across microarray platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

Minimizing the risk of reporting false positives in large-scale RNAi screens

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

Multiple-laboratory comparison of microarray platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.8.8.1037

10.2217/14622416.8.8.1037

21 January 2018

Identifiers

DOI

1 reference

25 July 2017

1 reference