(Q33304630)

25 July 2017

1 reference

title

Mutant huntingtin can paradoxically protect neurons from death (English)

1 reference

25 July 2017

T Zuchner

1

1 reference

25 July 2017

P Brundin

series ordinal

2

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25 July 2017

publication date

2 November 2007

1 reference

Cell Death & Differentiation

25 July 2017

published in

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25 July 2017

volume

15

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25 July 2017

issue

3

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25 July 2017

page(s)

435-442

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Selective sparing of a class of striatal neurons in Huntington's disease

25 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Huntingtin localization in brains of normal and Huntington's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Regulation of proteins affecting NMDA receptor-induced excitotoxicity in a Huntington's mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Wild-type huntingtin protects neurons from excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Recent advances on the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Mice transgenic for the Huntington's disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Mice transgenic for the human Huntington's disease mutation have reduced sensitivity to kainic acid toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Huntington's disease transgenic mice are resistant to global cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Polyglutamine expansion of huntingtin impairs its nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Huntingtin interacts with cystathionine beta-synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Brain-derived neurotrophic factor inhibits apoptosis and dopamine-induced free radical production in striatal neurons but does not prevent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

'Ischemic tolerance' phenomenon found in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

NMDA receptor antagonism, but not AMPA receptor antagonism attenuates induced ischaemic tolerance in the gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

MK-801, but not anisomycin, inhibits the induction of tolerance to ischemia in the gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

1 reference

7 January 2021

Neuropathological classification of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

7 January 2021

Effects of ciliary neurotrophic factor on excitotoxicity and calcium-ionophore A23187-induced cell death in cultured embryonic striatal neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402261

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402261

1 reference

25 July 2017

1 reference