(Q42513393)

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Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene

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Europe PubMed Central

PubMed publication ID

1 November 2017

Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene (English)

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Europe PubMed Central

PubMed publication ID

1 November 2017

Huntington's disease

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1

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Europe PubMed Central

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1 November 2017

author name string

Guatteo E

2

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Europe PubMed Central

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1 November 2017

Mercuri NB

3

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Europe PubMed Central

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1 November 2017

Bernardi G

4

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Europe PubMed Central

PubMed publication ID

1 November 2017

Li XJ

5

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Europe PubMed Central

PubMed publication ID

1 November 2017

Castilho RF

6

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1 November 2017

Brundin P

7

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1 November 2017

language of work or name

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publication date

1 November 2001

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Europe PubMed Central

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1 November 2017

European Journal of Neuroscience

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Europe PubMed Central

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1 November 2017

14

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Europe PubMed Central

PubMed publication ID

1 November 2017

9

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Europe PubMed Central

PubMed publication ID

1 November 2017

1492-1504

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Europe PubMed Central

PubMed publication ID

1 November 2017

CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Neuronal calcium signaling

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Quantitative evaluation of mitochondrial calcium content in rat cortical neurones following a glutamate stimulus

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: implications for ischemia and Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Neurophysiological, pharmacological and morphological properties of human caudate neurons recorded in vitro

1 reference

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21 January 2018

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

1 reference

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21 January 2018

Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Excitotoxic injury of the neostriatum: a model for Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

An immunohistochemical investigation of the human neostriatum in Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Mice transgenic for the Huntington's disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

The role of intracellular Na+ and mitochondria in buffering of kainate-induced intracellular free Ca2+ changes in rat forebrain neurones.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Early alterations in gene expression and cell morphology in a mouse model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Membrane properties and synaptic responses of rat striatal neurones in vitro

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Preconditioning in vivo ischemia inhibits anoxic long-term potentiation and functionally protects CA1 neurons in the gerbil

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Mice transgenic for the human Huntington's disease mutation have reduced sensitivity to kainic acid toxicity

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Effects of pretreatment with sublethal ischemia on the extracellular glutamate concentrations during secondary ischemia in the gerbil hippocampus evaluated with intracerebral microdialysis

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Calcium movement in ischemia-tolerant hippocampal CA1 neurons after transient forebrain ischemia in gerbils

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Molecular mechanisms of calcium-dependent excitotoxicity

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Splice variants of glutamate receptor subunits 2 and 3 in striatal projection neurons

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Ischemic preconditioning in humans: models, mediators, and clinical relevance

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Huntington disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Reduced Striatal [3H]Inositol 1,4,5-Trisphosphate Binding in Huntington's Disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Additive Effects of Caspase Inhibitor and Lazaroid on the Survival of Transplanted Rat and Human Embryonic Dopamine Neurons

1 reference

https://api.crossref.org/works/10.1046%2FJ.0953-816X.2001.01767.X

21 January 2018

Identifiers

10.1046/J.0953-816X.2001.01767.X

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

ResearchGate publication ID

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