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Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance.
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PMCID
2268427
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1 January 2020
title
Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance
(English)
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2268427
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1 January 2020
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Kalpana Kannan
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2268427
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1 January 2020
Andrew D. Nelson
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2268427
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1 January 2020
Dorothy E. Shippen
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Dorothy E Shippen
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2268427
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1 January 2020
language of work or name
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22 January 2008
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2268427
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1 January 2020
published in
Molecular and Cellular Biology
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2268427
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18212040%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
volume
28
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Europe PubMed Central
PMCID
2268427
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18212040%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
issue
7
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Europe PubMed Central
PMCID
2268427
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1 January 2020
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2332-2341
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2268427
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1 January 2020
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ImageQuant
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2268427/fullTextXML
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cites work
Arabidopsis CBF5 interacts with the H/ACA snoRNP assembly factor NAF1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Protein composition of catalytically active human telomerase from immortal cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The POT1-TPP1 telomere complex is a telomerase processivity factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Telomere rapid deletion regulates telomere length in Arabidopsis thaliana
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Are mouse telomeres going to pot?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The biogenesis and regulation of telomerase holoenzymes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The role of the nonhomologous end-joining DNA double-strand break repair pathway in telomere biology
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The effect of TERC haploinsufficiency on the inheritance of telomere length
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Making the most of a little: dosage effects in eukaryotic telomere length maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The many facets of H/ACA ribonucleoproteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Telomerase RNA structure and function: implications for dyskeratosis congenita.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Targeted disruption of Dkc1, the gene mutated in X-linked dyskeratosis congenita, causes embryonic lethality in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Haploinsufficiency of mTR results in defects in telomere elongation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Functional multimerization of the human telomerase reverse transcriptase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Living with genome instability: plant responses to telomere dysfunction
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
A telomerase component is defective in the human disease dyskeratosis congenita
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
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21 June 2018
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
21 June 2018
Mapping and characterization of the X-linked dyskeratosis congenita (DKC) gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
21 June 2018
X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
21 June 2018
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
21 June 2018
Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
21 June 2018
Characterization and developmental patterns of telomerase expression in plants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
21 June 2018
Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Plant telomere biology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Synchronous Arabidopsis suspension cultures for analysis of cell-cycle gene activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Cloning and characterization of Arabidopsis thaliana AtNAP57--a homologue of yeast pseudouridine synthase Cbf5p.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
Nucleolus-associated telomere clustering and pairing precede meiotic chromosome synapsis in Arabidopsis thaliana
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268427
retrieved
31 October 2018
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18212040
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Length regulation and dynamics of individual telomere tracts in wild-type Arabidopsis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18212040
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A C-terminal Myb extension domain defines a novel family of double-strand telomeric DNA-binding proteins in Arabidopsis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18212040
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nonradioactive detection of telomerase activity using the telomeric repeat amplification protocol
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18212040
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.01490-07
1 reference
stated in
Europe PubMed Central
PMCID
2268427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18212040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PMCID
2268427
1 reference
stated in
Europe PubMed Central
PMCID
2268427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18212040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PubMed ID
18212040
1 reference
stated in
Europe PubMed Central
PMCID
2268427
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18212040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
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