(Q33321335)

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Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically

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Europe PubMed Central

PubMed publication ID

25 July 2017

Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically (English)

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Europe PubMed Central

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25 July 2017

Alzheimer's disease

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Lary C Walker

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author name string

Cansu Agca

1

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Europe PubMed Central

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25 July 2017

Jason J Fritz

2

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Europe PubMed Central

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25 July 2017

Allan I Levey

4

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Europe PubMed Central

PubMed publication ID

25 July 2017

Anthony Ws Chan

5

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Europe PubMed Central

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25 July 2017

James J Lah

6

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Europe PubMed Central

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25 July 2017

Yuksel Agca

7

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Europe PubMed Central

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25 July 2017

publication date

26 February 2008

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Europe PubMed Central

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25 July 2017

BMC Neuroscience

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Europe PubMed Central

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25 July 2017

9

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Europe PubMed Central

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25 July 2017

28

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Europe PubMed Central

PubMed publication ID

25 July 2017

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Creative Commons Attribution 2.0 Generic

26 February 2008

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April 2022 Public Data File from Crossref

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April 2022 Public Data File from Crossref

The coding sequence of amyloid-beta precursor protein APP contains a neural-specific promoter element

1 reference

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21 June 2018

Transgenic modifications of the rat genome

1 reference

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21 June 2018

Mouse models of Alzheimer's disease: insight into treatment

1 reference

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21 June 2018

Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats

1 reference

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21 June 2018

Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice

1 reference

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Real-time imaging of nuclear permeation by EGFP in single intact cells

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Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits

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Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

1 reference

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21 June 2018

Annual incidence of Alzheimer disease in the United States projected to the years 2000 through 2050.

1 reference

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

1 reference

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21 June 2018

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

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21 June 2018

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

1 reference

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21 June 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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21 June 2018

Transgenesis in rats: technical aspects and models

1 reference

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21 June 2018

The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

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Superovulation of immature rats by continuous infusion of follicle-stimulating hormone.

1 reference

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21 June 2018

Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

21 June 2018

Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

31 October 2018

A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

31 October 2018

Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

31 October 2018

Rat transgenic models with a phenotype of intracellular Abeta accumulation in hippocampus and cortex

1 reference

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Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor

1 reference

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31 October 2018

Genetic background regulates -amyloid precursor protein processing and -amyloid deposition in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268936

31 October 2018

Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

1 reference

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Monogenetic determinants of Alzheimer's disease: APP mutations

1 reference

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31 October 2018

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10.1186/1471-2202-9-28

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Europe PubMed Central

PubMed publication ID

25 July 2017

Dimensions Publication ID

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https://scigraph.springernature.com/pub.10.1186/1471-2202-9-28

9 September 2019

PMC publication ID

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Europe PubMed Central

PubMed publication ID

25 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

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