(Q33323380)

English

The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by ring finger domain

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 July 2017

The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by ring finger domain (English)

1 reference

Europe PubMed Central

25 July 2017

Tomokazu Fukuda

object named as

Tomokazu Fukuda

1

0 references

author name string

Yasuyuki Kondo

2

1 reference

Europe PubMed Central

25 July 2017

Hitoshi Nakagama

3

1 reference

Europe PubMed Central

25 July 2017

language of work or name

0 references

publication date

12 March 2008

1 reference

Europe PubMed Central

25 July 2017

1 reference

Europe PubMed Central

25 July 2017

3

1 reference

Europe PubMed Central

25 July 2017

e1776

1 reference

Europe PubMed Central

25 July 2017

3

1 reference

Europe PubMed Central

25 July 2017

copyright license

Creative Commons Attribution 4.0 International

12 March 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

RING domain-mediated interaction is a requirement for MDM2's E3 ligase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Chfr is required for tumor suppression and Aurora A regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Chfr inactivation is not associated to chromosomal instability in colon cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Critical contribution of the MDM2 acidic domain to p53 ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Epigenetic inactivation of CHFR in human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Frequent hypermethylation of the 5' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

EL5, a rice N-acetylchitooligosaccharide elicitor-responsive RING-H2 finger protein, is a ubiquitin ligase which functions in vitro in co-operation with an elicitor-responsive ubiquitin-conjugating enzyme, OsUBC5b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

A murine model of Nijmegen breakage syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Mitotic kinases as regulators of cell division and its checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

21 June 2018

Promoter methylation and response to chemotherapy and radiation in esophageal cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

The CHFR mitotic checkpoint protein delays cell cycle progression by excluding Cyclin B1 from the nucleus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

Targeting polo-like kinase 1 for cancer therapy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

Aberrant hypermethylation of the promoter region of the CHFR gene is rare in primary breast cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

Requirements for the destruction of human Aurora-A.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001776

21 January 2018

CpG island promoter hypermethylation of the pro-apoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

31 October 2018

Aberrant methylation of the CHFR gene is frequently detected in non-invasive colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

31 October 2018

DNA methylation of CHFR is not a predictor of the response to docetaxel and paclitaxel in advanced and recurrent gastric cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

31 October 2018

p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: further evidence of CHK2 in inherited cancer predisposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258000

31 October 2018

Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18335050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18335050

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0001776

1 reference

Europe PubMed Central

25 July 2017

2008PLoSO...3.1776F

0 references

1 reference

Europe PubMed Central

25 July 2017

1 reference

Europe PubMed Central

25 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33323380&oldid=1871671290"