(Q33325589)

25 July 2017

title

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners (English)

1 reference

25 July 2017

author name string

Christopher J Oldfield

1

1 reference

25 July 2017

Jingwei Meng

2

1 reference

25 July 2017

Jack Y Yang

3

1 reference

25 July 2017

Mary Qu Yang

4

1 reference

25 July 2017

A Keith Dunker

6

1 reference

25 July 2017

language of work or name

English

0 references

publication date

1 January 2008

1 reference

25 July 2017

1 reference

25 July 2017

volume

9 Suppl 1

1 reference

25 July 2017

page(s)

S1

1 reference

Mining alpha-helix-forming molecular recognition features with cross species sequence alignments

25 July 2017

cites work

1 reference

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21 June 2018

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Characterization of molecular recognition features, MoRFs, and their binding partners

21 June 2018

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21 June 2018

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Local structural disorder imparts plasticity on linear motifs.

21 June 2018

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Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs

21 June 2018

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Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins

21 June 2018

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Relating three-dimensional structures to protein networks provides evolutionary insights

21 June 2018

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Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits

21 June 2018

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Intrinsic disorder and functional proteomics

21 June 2018

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Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor

21 June 2018

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Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

21 June 2018

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What properties characterize the hub proteins of the protein-protein interaction network of Saccharomyces cerevisiae?

21 June 2018

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Intrinsic disorder in transcription factors

21 June 2018

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Length-dependent prediction of protein intrinsic disorder.

21 June 2018

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Recognition of enolase in the Escherichia coli RNA degradosome

21 June 2018

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Target structure-based discovery of small molecules that block human p53 and CREB binding protein association

21 June 2018

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Intrinsic protein disorder, amino acid composition, and histone terminal domains.

21 June 2018

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Systematic discovery of new recognition peptides mediating protein interaction networks

21 June 2018

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Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3

21 June 2018

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Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A

21 June 2018

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Flexible nets. The roles of intrinsic disorder in protein interaction networks.

21 June 2018

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Rho GTPases: biochemistry and biology

21 June 2018

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Exploiting heterogeneous sequence properties improves prediction of protein disorder.

21 June 2018

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Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling

21 June 2018

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Scaffold proteins dictate Rho GTPase-signaling specificity

21 June 2018

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Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding.

21 June 2018

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Linear motifs: evolutionary interaction switches.

21 June 2018

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Addressing the intrinsic disorder bottleneck in structural proteomics.

21 June 2018

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Comparative interactomics

21 June 2018

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The links between axin and carcinogenesis

21 June 2018

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STRING: known and predicted protein-protein associations, integrated and transferred across organisms

21 June 2018

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AKAP signalling complexes: focal points in space and time

21 June 2018

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Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation

21 June 2018

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Regulation of p53 activity through lysine methylation

21 June 2018

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Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

21 June 2018

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Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E.

21 June 2018

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POINT: a database for the prediction of protein-protein interactions based on the orthologous interactome

21 June 2018

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PathBLAST: a tool for alignment of protein interaction networks

21 June 2018

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Protein interaction networks from yeast to human

21 June 2018

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Evidence for dynamically organized modularity in the yeast protein-protein interaction network

21 June 2018

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Back to the biology in systems biology: what can we learn from biomolecular networks?

21 June 2018

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A method for simultaneous alignment of multiple protein structures

21 June 2018

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Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

21 June 2018

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Overproduction, crystallization and preliminary crystallographic analysis of a novel human DNA-repair enzyme that recognizes oxidative DNA damage

21 June 2018

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Structural basis for the attachment of a paramyxoviral polymerase to its template

21 June 2018

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Tethering: fragment-based drug discovery

21 June 2018

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Unlocking the code of 14-3-3.

21 June 2018

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Axin: a master scaffold for multiple signaling pathways

21 June 2018

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21 June 2018

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The importance of intrinsic disorder for protein phosphorylation

21 June 2018

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Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

21 June 2018

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Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways

21 June 2018

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14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking

21 June 2018

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Network biology: understanding the cell's functional organization

21 June 2018

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21 June 2018

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Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates

21 June 2018

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21 June 2018

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21 June 2018

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The N-terminal domain of p53 is natively unfolded.

21 June 2018

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21 June 2018

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A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders

21 June 2018

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ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

21 June 2018

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Solution structure, dynamics, and thermodynamics of the native state ensemble of the Sem-5 C-terminal SH3 domain

21 June 2018

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Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces

21 June 2018

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Extended disordered proteins: targeting function with less scaffold

21 June 2018

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Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet

21 June 2018

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Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

21 June 2018

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Structure of a Sir2 enzyme bound to an acetylated p53 peptide

21 June 2018

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Intrinsic disorder in cell-signaling and cancer-associated proteins

21 June 2018

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Analyzing yeast protein-protein interaction data obtained from different sources

21 June 2018

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Classification of scale-free networks

21 June 2018

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Intrinsic disorder and protein function

21 June 2018

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Comparative assessment of large-scale data sets of protein-protein interactions

21 June 2018

1 reference

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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

21 June 2018

1 reference

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Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

21 June 2018

1 reference

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Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2

21 June 2018

1 reference

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Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

21 June 2018

1 reference

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Identification of intrinsic order and disorder in the DNA repair protein XPA.

21 June 2018

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Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation

21 June 2018

1 reference

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Lethality and centrality in protein networks

21 June 2018

1 reference

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A comprehensive two-hybrid analysis to explore the yeast protein interactome

21 June 2018

1 reference

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BALL--rapid software prototyping in computational molecular biology. Biochemicals Algorithms Library

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Sequence complexity of disordered protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Error and attack tolerance of complex networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Solution structure of a dynein motor domain associated light chain

21 June 2018

1 reference

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Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

From molecular to modular cell biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide

21 June 2018

1 reference

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The atomic structure of protein-protein recognition sites

21 June 2018

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14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove

21 June 2018

1 reference

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Collective dynamics of 'small-world' networks

21 June 2018

1 reference

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The structural basis for 14-3-3:phosphopeptide binding specificity

21 June 2018

1 reference

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Analysis of protein-protein interaction sites using surface patches

21 June 2018

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 June 2018

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Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Principles of protein-protein interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Modulation of calmodulin plasticity in molecular recognition on the basis of x-ray structures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

PHD--an automatic mail server for protein secondary structure prediction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Protein-protein interactions: a review of protein dimer structures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

p53 mutations in human cancers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Analysis of chameleon sequences and their implications in biological processes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Disorder and sequence repeats in hub proteins and their implications for network evolution.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Protein intrinsic disorder and human papillomaviruses: increased amount of disorder in E6 and E7 oncoproteins from high risk HPVs.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Intrinsic disorder is a key characteristic in partners that bind 14-3-3 proteins.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Coupled folding and binding with alpha-helix-forming molecular recognition elements

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Conformational prerequisites for formation of amyloid fibrils from histones

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Structural basis for the mechanism and regulation of Sir2 enzymes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

The C-terminal domain of measles virus nucleoprotein belongs to the class of intrinsically disordered proteins that fold upon binding to their physiological partner

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Structural disorder and modular organization in Paramyxovirinae N and P.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

31 October 2018

An RNA-binding chameleon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Predictions of protein segments with the same aminoacid sequence and different secondary structure: a benchmark for predictive methods.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Protein disorder and the evolution of molecular recognition: theory, predictions and observations

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Prediction of protein-protein interaction sites using patch analysis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Effect of sampling on topology predictions of protein-protein interaction networks

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386051

High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds

10 December 2018

1 reference

12 December 2020

The disordered amino-terminus of SIMPL interacts with members of the 70-kDa heat-shock protein family

1 reference

12 December 2020

Analysis of chameleon sequences by energy decomposition on a pairwise per-residue basis

1 reference

12 December 2020

The relationship between the flexibility of proteins and their conformational states on forming protein-protein complexes with an application to protein-protein docking

1 reference

12 December 2020

Abundance of intrinsic disorder in protein associated with cardiovascular disease

1 reference

12 December 2020

Intrinsic unstructuredness and abundance of PEST motifs in eukaryotic proteomes

1 reference

12 December 2020

Chameleon sequences in the PDB

1 reference

12 December 2020

Predicting Binding Regions within Disordered Proteins

1 reference

12 December 2020

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53

1 reference

12 December 2020

Another window into disordered protein function

1 reference

12 December 2020

Comparative genomics of centrality and essentiality in three eukaryotic protein-interaction networks

1 reference

12 December 2020

Disordered domains and high surface charge confer hubs with the ability to interact with multiple proteins in interaction networks

1 reference

12 December 2020

Optimizing long intrinsic disorder predictors with protein evolutionary information

1 reference

12 December 2020

Calmodulin signaling: analysis and prediction of a disorder-dependent molecular recognition

1 reference

12 December 2020

BRCA1: a scaffold for p53 response?

1 reference

12 December 2020

Context-dependent secondary structure formation of a designed protein sequence

1 reference

12 December 2020

1 reference

12 December 2020

Structural invariants in protein folding

1 reference

12 December 2020

Predicting Protein Disorder for N-, C-, and Internal Regions

1 reference

12 December 2020

Morphology of protein-protein interfaces.

1 reference

12 December 2020

10.1186/1471-2164-9-S1-S1

Identifiers

DOI

1 reference

Dimensions Publication ID

25 July 2017

0 references

1 reference

25 July 2017

1 reference