(Q33327656)

25 July 2017

title

Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L (English)

1 reference

25 July 2017

Donna M Huryn

9

0 references

Elizabeth R Sharlow

7

object named as

Elizabeth R Sharlow

1 reference

25 July 2017

8

Andrew D Napper

1 reference

25 July 2017

Parag P Shah

1

1 reference

25 July 2017

Michael C Myers

2

1 reference

25 July 2017

Mary Pat Beavers

3

1 reference

25 July 2017

Jeremy E Purvis

4

1 reference

25 July 2017

Huiyan Jing

5

1 reference

25 July 2017

Heather J Grieser

6

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25 July 2017

Barry S Cooperman

10

1 reference

25 July 2017

Amos B Smith

11

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25 July 2017

Scott L Diamond

12

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25 July 2017

publication date

10 April 2008

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25 July 2017

published in

Molecular Pharmacology

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25 July 2017

volume

74

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25 July 2017

issue

1

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25 July 2017

page(s)

34-41

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Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor

25 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Cathepsin L is involved in proteolytic processing of the Hendra virus fusion protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Family C1 cysteine proteases: biological diversity or redundancy?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Lysosomal cysteine proteases (cathepsins): promising drug targets.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Lysosomal cysteine proteases: facts and opportunities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Azapeptides as inhibitors and active site titrants for cysteine proteinases.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Design of potent and selective human cathepsin K inhibitors that span the active site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

The crystal structure of human cathepsin L complexed with E-64

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

Cysteine protease inhibition by azapeptide esters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

A detailed comparison of current docking and scoring methods on systems of pharmaceutical relevance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575030

From good substrates to good inhibitors: design of inhibitors for serine and thiol proteases

31 October 2018

1 reference

12 December 2020

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

1 reference

12 December 2020

Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

1 reference

12 December 2020

Cysteine Proteases and Their Inhibitors

1 reference

12 December 2020

Triggering of apoptosis by cathepsins

1 reference

12 December 2020

Identifiers

DOI

10.1124/MOL.108.046219

1 reference

25 July 2017

1 reference

25 July 2017

1 reference