(Q33328676)

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Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 July 2017

Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

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8

object named as

Alain Milon

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Virginie Gervais

object named as

Virginie Gervais

3

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author name string

Corinne Hazan

1

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

François Boudsocq

2

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Olivier Saurel

4

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Marion Ciais

5

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Christophe Cazaux

6

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Jerzy Czaplicki

7

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

publication date

16 April 2008

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Europe PubMed Central

PubMed publication ID

25 July 2017

BMC Structural Biology

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Europe PubMed Central

PubMed publication ID

25 July 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

1 reference

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Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells.

1 reference

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Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities

2 references

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A decade of fragment-based drug design: strategic advances and lessons learned

1 reference

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Activities and mechanism of DNA polymerase beta

1 reference

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The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

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The DNA-polymerase-X family: controllers of DNA quality?

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Using NMRView to visualize and analyze the NMR spectra of macromolecules

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Saturation transfer difference NMR spectroscopy for identifying ligand epitopes and binding specificities

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Studies of protein–ligand interactions by NMR

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DNA polymerase beta and mammalian base excision repair.

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Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

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Mammalian DNA beta-polymerase in base excision repair of alkylation damage.

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Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

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XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair

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DNA polymerase beta is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide.

1 reference

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The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

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Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity

1 reference

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High-throughput nuclear magnetic resonance-based screening

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Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage

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Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities

1 reference

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The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta

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21 June 2018

Discovering high-affinity ligands for proteins: SAR by NMR

1 reference

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Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis

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Automated docking of flexible ligands: applications of AutoDock

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The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA.

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Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

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Three-dimensional NMR spectroscopy of a protein in solution

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The inhibitory action of fatty acids on DNA polymerase beta

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Assignments of 1H, 15N, and 13C resonances for the backbone and side chains of the N-terminal domain of DNA polymerase beta. Determination of the secondary structure and tertiary contacts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18416825

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The Efficiency and Fidelity of Translesion Synthesis past Cisplatin and Oxaliplatin GpG Adducts by Human DNA Polymerase β

1 reference

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Identifiers

10.1186/1472-6807-8-22

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

ResearchGate publication ID

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