(Q33331198)

25 July 2017

title

Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells (English)

1 reference

25 July 2017

0 references

Ricky Malhotra

1

1 reference

25 July 2017

David W Tyson

series ordinal

2

1 reference

25 July 2017

Henry M Rosevear

series ordinal

3

1 reference

25 July 2017

Frank C Brosius

series ordinal

4

1 reference

25 July 2017

publication date

30 April 2008

1 reference

BMC Cardiovascular Disorders

25 July 2017

published in

1 reference

25 July 2017

volume

8

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25 July 2017

page(s)

9

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Creative Commons Attribution 2.0 Generic

25 July 2017

copyright license

start time

30 April 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2261-8-9

0 references

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

21 June 2018

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21 June 2018

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 June 2018

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Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax.

21 June 2018

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Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism

21 June 2018

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Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function

21 June 2018

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Inhibition of hypoxia inducible factor 1alpha causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells

21 June 2018

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CoCl2, a chemical inducer of hypoxia-inducible factor-1, and hypoxia reduce apoptotic cell death in hepatoma cell line HepG2.

21 June 2018

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Glucose uptake and adenoviral mediated GLUT1 infection decrease hypoxia-induced HIF-1alpha levels in cardiac myocytes

21 June 2018

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21 June 2018

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Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death

21 June 2018

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HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.

21 June 2018

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Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 June 2018

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Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

21 June 2018

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2387135

Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes

21 June 2018

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 June 2018

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

21 June 2018

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 June 2018

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2387135

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 June 2018

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c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.

21 June 2018

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Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

21 January 2018

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Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia.

21 January 2018

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Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes

21 January 2018

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Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury

21 January 2018

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Upregulation of GLUT1 expression is necessary for hypertrophy and survival of neonatal rat cardiomyocytes

21 January 2018

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Functionality of hypoxia-induced BAX expression in a human glioblastoma xenograft model

21 January 2018

1 reference

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Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: role of Bcl-2, Bcl-xL and Bax in tubular injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2387135

Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2387135

Reperfusion injury on cardiac myocytes after simulated ischemia

31 October 2018

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12 December 2020

Hypoxia-inducible factor 1: master regulator of O2 homeostasis

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12 December 2020

Expression of constitutively stable hybrid hypoxia-inducible factor-1alpha protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury

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12 December 2020

Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes

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12 December 2020

High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway

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12 December 2020

A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells

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12 December 2020

Oxidized low-density lipoprotein stimulates p53-dependent activation of proapoptotic Bax leading to apoptosis of differentiated endothelial progenitor cells

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12 December 2020

Identifiers

DOI

10.1186/1471-2261-8-9

1 reference

Dimensions Publication ID

25 July 2017

0 references

1 reference

25 July 2017

1 reference