(Q33347664)

26 July 2017

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title

The role of genetic variation in the causation of mental illness: an evolution-informed framework (English)

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26 July 2017

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R Uher

1

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language of work or name

English

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publication date

25 August 2009

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26 July 2017

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26 July 2017

volume

14

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26 July 2017

issue

12

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26 July 2017

page(s)

1072-1082

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Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

26 July 2017

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The future of genetic studies of complex human diseases

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What can genome-wide association studies tell us about the genetics of common disease?

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Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

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Identification of loci associated with schizophrenia by genome-wide association and follow-up

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Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

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Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best?

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Fermenting fruit and the historical ecology of ethanol ingestion: is alcoholism in modern humans an evolutionary hangover?

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Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

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Schizophrenia: a concise overview of incidence, prevalence, and mortality

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Cross-national epidemiology of major depression and bipolar disorder

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The epidemiology of depression in metropolitan China.

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Heterogeneity in Incidence Rates of Schizophrenia and Other Psychotic Syndromes

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The incidence of anorexia nervosa on Curaçao

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Death by homicide, suicide, and other unnatural causes in people with mental illness: a population-based study.

21 January 2018

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Deaths from natural causes in people with mental illness: a cohort study.

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Excess mortality, causes of death and prognostic factors in anorexia nervosa

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Mental disorders and cause-specific mortality.

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Mortality and causes of death in autism spectrum disorders: an update

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Causes of death in autism

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Mortality associated with depression: a forty-year perspective from the Stirling County Study

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Is perceived nervousness and anxiety a predictor of premature mortality and severe morbidity? A longitudinal follow up of the Swedish survey of living conditions

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Excess mortality among 3302 patients with 'pure' anxiety neurosis

21 January 2018

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Anorexia nervosa and motherhood: reproduction pattern and mothering behavior of 50 women

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Fertility of first-degree relatives of patients with schizophrenia: a three generation perspective.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Differential fertility in bipolar affective illness

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Mood disorders and fertility in women: a critical review of the literature and implications for future research

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Mortality Risk Among Offspring of Psychiatric Inpatients: A Population-Based Follow-Up to Early Adulthood

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Offspring of Depressed Parents: 20 Years Later

21 January 2018

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Disease susceptibility genes for autism

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Infantile autism: a genetic study of 21 twin pairs

21 January 2018

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High Concordance of Bipolar I Disorder in a Nationwide Sample of Twins

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Prevalence, heritability, and prospective risk factors for anorexia nervosa

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Genetic epidemiology of major depression: review and meta-analysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

A hospital-based twin register of the heritability of DSM-IV unipolar depression

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

A review and meta-analysis of the genetic epidemiology of anxiety disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Flexibility in a gene network affecting a simple behavior in Drosophila melanogaster

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Forum: The case for gene-environment interactions in psychiatry.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Variance components models for gene-environment interaction in quantitative trait locus linkage analysis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

The equal environments assumption of classical twin studies may not hold

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

21 January 2018

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The origins, patterns and implications of human spontaneous mutation

21 January 2018

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Development. There's something curious about paternal-age effects

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Raised parental age in psychiatric patients: evidence for the constitutional hypothesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

A comparison of selected risk factors for unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia from a danish population-based cohort

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FMP.2009.85

21 January 2018

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Advancing paternal age and autism

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Advanced parental age and the risk of autism spectrum disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Advancing paternal age and the risk of schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Advancing Paternal Age and Bipolar Disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Natural selection and the elusiveness of happiness

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Adapted to flee famine: Adding an evolutionary perspective on anorexia nervosa

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

The rise and fall of the common disease-common variant (CD-CV) hypothesis: how the sickle cell disease paradigm led us all astray (or did it?).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

An evolutionary framework for common diseases: the ancestral-susceptibility model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The stigma of mental illness in Asian cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Perception of stigma among family members of individuals with schizophrenia and major affective disorders in rural Ethiopia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Are rare variants responsible for susceptibility to complex diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FMP.2009.85

21 January 2018

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Fitness consequences of avian personalities in a fluctuating environment.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

A stochastic model concerning the maintenance of genetic variability in quantitative characters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Most rare missense alleles are deleterious in humans: implications for complex disease and association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Paternal age and sporadic schizophrenia: evidence for de novo mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Chromosomal abnormalities and mental illness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Genetics of austim: complex aetiology for a heterogeneous disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Strong association of de novo copy number mutations with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Strategy for investigating interactions between measured genes and measured environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Degeneracy and complexity in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The implications of gene-environment interactions in depression: will cause inform cure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Stressful life events, genetic liability, and onset of an episode of major depression in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The 'common disease-common variant' hypothesis and familial risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The influence of family structure, the TPH2 G-703T and the 5-HTTLPR serotonergic genes upon affective problems in children aged 10-14 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

MAOA, maltreatment, and gene–environment interaction predicting children's mental health: new evidence and a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Gene-environment interactions in depression research: genetic polymorphisms and life-stress polyprocedures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Statistical difficulties of detecting interactions and moderator effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Invited commentary: from genome-wide association studies to gene-environment-wide interaction studies--challenges and opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Two-stage analysis for gene-environment interaction utilizing both case-only and family-based analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Gene-environment interaction in genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Generalized linear modeling with regularization for detecting common disease rare haplotype association

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Once and Again—Issues Surrounding Replication in Genetic Association Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The structure of common mental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

A twin study of genetic relationships between psychotic symptoms

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.85

Major depression and generalized anxiety disorder. Same genes, (partly) different environments?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Quantifying the Slightly Deleterious Mutation Model of Molecular Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Fertility of Patients With Schizophrenia, Their Siblings, and the General Population: A Cohort Study From 1950 to 1959 in Finland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

Depression and social stress in Pakistan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

The new genomics: global views of biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts

1 reference

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The sociobiology of sociopathy: An integrated evolutionary model

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Cross-national epidemiology of major depression and bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Trends in hospital admissions for eating disorders in a country undergoing a socio-cultural transition, the Czech Republic 1981-2005.

1 reference

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7 January 2021

Excess mortality of mental disorder

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Subfecundity and anxiety in a nationally representative sample

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Mortality risk among offspring of psychiatric inpatients: a population-based follow-up to early adulthood

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Offspring of Depressed Parents: 20 Years Later

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studies

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Familial Resemblance and Heritability

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a 'thrifty' allele?

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

A framework for interpreting genome-wide association studies of psychiatric disorders

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.85

7 January 2021

Gene-environment interaction in complex diseases: asthma as an illustrative case.

1 reference

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7 January 2021

Identifiers

DOI

10.1038/MP.2009.85

1 reference

26 July 2017

1 reference