(Q33348048)

26 July 2017

title

T cell receptor triggering by force (English)

1 reference

26 July 2017

Zhengyu Ma

1

1 reference

26 July 2017

Terri H Finkel

series ordinal

2

1 reference

26 July 2017

publication date

1 January 2010

1 reference

26 July 2017

1 reference

26 July 2017

volume

31

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26 July 2017

issue

1

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26 July 2017

page(s)

1-6

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Endocytic regulation of Notch signaling

26 July 2017

cites work

1 reference

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Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

21 June 2018

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21 June 2018

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Transcellular diapedesis is initiated by invasive podosomes

21 June 2018

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Human TCR-binding affinity is governed by MHC class restriction

21 June 2018

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DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

21 June 2018

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Intercellular transfer of cell-surface proteins is common and can affect many stages of an immune response

21 June 2018

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Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits

21 June 2018

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Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

21 June 2018

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How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation

21 June 2018

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21 June 2018

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The kinetic-segregation model: TCR triggering and beyond

21 June 2018

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Mechanotransduction involving multimodular proteins: converting force into biochemical signals

21 June 2018

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Immune synapses in T-cell activation

21 June 2018

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How TCRs bind MHCs, peptides, and coreceptors

21 June 2018

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Deconstructing the form and function of the TCR/CD3 complex

21 June 2018

1 reference

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Modeling T cell antigen discrimination based on feedback control of digital ERK responses

21 June 2018

1 reference

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T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Twisting tails exposed: the evidence for TCR conformational change

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

The adhesion force of Notch with Delta and the rate of Notch signaling

21 June 2018

1 reference

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Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes

21 June 2018

1 reference

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Antigen presentation by the endothelium: a green light for antigen-specific T cell trafficking?

21 June 2018

1 reference

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A single class II myosin modulates T cell motility and stopping, but not synapse formation

21 June 2018

1 reference

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

21 June 2018

1 reference

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Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

21 June 2018

1 reference

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Regulation of constitutive TCR internalization by the zeta-chain.

21 June 2018

1 reference

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RIPping notch apart: a new role for endocytosis in signal transduction?

21 June 2018

1 reference

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Identification of self through two-dimensional chemistry and synapses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

The TCR triggering puzzle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation rates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

The role of lipid rafts in T cell antigen receptor (TCR) signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

TCR-Mediated internalization of peptide-MHC complexes acquired by T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Antigen presentation by T cells: T cell receptor ligation promotes antigen acquisition from professional antigen-presenting cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Regulation of antigen receptor signal transduction by protein tyrosine kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Cell migration: a physically integrated molecular process

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Spatial and temporal characteristics of the increase in intracellular Ca2+ induced in cytotoxic T lymphocytes by cellular antigen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Constitutive endocytosis and recycling of major histocompatibility complex class II glycoproteins in human B-lymphoblastoid cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Models for the Specific Adhesion of Cells to Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor zeta chain by the protein tyrosine kinase Lck.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Direct observation of ligand recognition by T cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Ligand recognition by alpha beta T cell receptors

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818226

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

31 October 2018

1 reference

12 December 2020

From TCR Engagement to T Cell Activation

1 reference

12 December 2020

T-cell activation is accompanied by an ubiquitination process occurring at the immunological synapse

1 reference

12 December 2020

Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

1 reference

12 December 2020

Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells

1 reference

12 December 2020

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition

1 reference

12 December 2020

TCR dynamics on the surface of living T cells

1 reference

12 December 2020

Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck

1 reference

12 December 2020

Identifiers

DOI

10.1016/J.IT.2009.09.008

1 reference

26 July 2017

1 reference

26 July 2017

1 reference