(Q33354798)

26 July 2017

title

Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer (English)

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26 July 2017

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6

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26 July 2017

Anne Kallioniemi

4

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author name string

Henna Heinonen

1

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26 July 2017

Anni Nieminen

2

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26 July 2017

Matti Saarela

3

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26 July 2017

Juha Klefström

5

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26 July 2017

Outi Monni

7

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26 July 2017

language of work or name

English

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publication date

24 July 2008

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26 July 2017

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26 July 2017

volume

9

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26 July 2017

page(s)

348

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https://scigraph.springernature.com/pub.10.1186/1471-2164-9-348

26 July 2017

exact match

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cites work

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21 June 2018

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Inhibiting the phosphoinositide 3-kinase pathway for cancer treatment

21 June 2018

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Determinants of rapamycin sensitivity in breast cancer cells

21 June 2018

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Alterations of INK4a(p16-p14ARF)/INK4b(p15) expression and telomerase activation in meningioma progression

21 June 2018

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Anti-Her-2/neu antibody induces apoptosis in Her-2/neu overexpressing breast cancer cells independently from p53 status

21 June 2018

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 June 2018

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p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

21 June 2018

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Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer

21 June 2018

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

21 June 2018

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Multiple genes at 17q23 undergo amplification and overexpression in breast cancer

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis

21 June 2018

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 June 2018

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The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

21 June 2018

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PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer.

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

31 October 2018

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Phospholipase D confers rapamycin resistance in human breast cancer cells

31 October 2018

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Impact of DNA amplification on gene expression patterns in breast cancer

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

Novel therapeutic approach: ligands for PPARgamma and retinoid receptors induce apoptosis in bcl-2-positive human breast cancer cells

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

Drosophila S6 kinase: a regulator of cell size

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2496917

A gene transcription signature of the Akt/mTOR pathway in clinical breast tumors

31 October 2018

1 reference

12 December 2020

Transcription inhibitors stimulate translation of 5' TOP mRNAs through activation of S6 kinase and the mTOR/FRAP signalling pathway

1 reference

12 December 2020

Complex response of breast epithelial cell lines to topoisomerase inhibitors

1 reference

12 December 2020

Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer

1 reference

12 December 2020

Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2164-9-348

1 reference

Dimensions Publication ID

26 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-9-348

9 September 2019

1 reference

26 July 2017

1 reference