(Q27628650)

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

Len Stephens

4

0 references

Matthias P Wymann

1 reference

ORCID Public Data File 2021

author name string

Edward H. Walker

1

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

Michael E. Pacold

2

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

Olga Perisic

3

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

Philip T. Hawkins

5

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

Matthias P. Wymann

6

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

Roger L. Williams

7

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

language of work or name

English

0 references

publication date

October 2000

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

volume

6

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

page(s)

909-919

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https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

25 May 2017

issue

4

1 reference

https://doi.org/10.1016%2FS1097-2765%2805%2900089-4

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

25 May 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

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7 January 2021

Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues

1 reference

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7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

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7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

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7 January 2021

Synthesis and in vitro evaluation of new wortmannin esters: potent inhibitors of phosphatidylinositol 3-kinase

1 reference

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7 January 2021

Using structure to define the function of phosphoinositide 3-kinase family members

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Flavonoids and the inhibition of PKC and PI 3-kinase

1 reference

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7 January 2021

ATP site-directed competitive and irreversible inhibitors of protein kinases

1 reference

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7 January 2021

Phospatidylinositol 3-kinase expression in human breast cancer

1 reference

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7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

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7 January 2021

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

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7 January 2021

Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits

1 reference

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7 January 2021

Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine

1 reference

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7 January 2021

Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

1 reference

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7 January 2021

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

1 reference

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7 January 2021

Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma

1 reference

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7 January 2021

The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs

1 reference

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7 January 2021

Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2

1 reference

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7 January 2021

Raster3D: photorealistic molecular graphics

1 reference

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7 January 2021

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

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7 January 2021

Studies on the mechanism of phosphatidylinositol 3-kinase inhibition by wortmannin and related analogs

1 reference

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7 January 2021

Staurosporine, a potentially important gift from a microorganism.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors.

1 reference

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7 January 2021

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetin.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: structure-activity analysis and interactions with wortmannin.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Signaling by distinct classes of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Structural insights into phosphoinositide 3-kinase catalysis and signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2805%2900089-4

7 January 2021

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

1 reference

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7 January 2021