(Q33373153)

English

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism.

scientific article

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828900%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828900%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

based on heuristic

inferred from title

linkage disequilibrium

1 reference

based on heuristic

inferred from title

Andrew J. Cassidy

4

1 reference

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15 January 2020

9

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15 January 2020

10

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15 January 2020

author name string

Fiona E M Paulin

1

1 reference

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15 January 2020

Mary O'Neill

2

1 reference

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15 January 2020

Gillian McGregor

3

1 reference

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15 January 2020

Alison Ashfield

5

1 reference

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15 January 2020

Clinton W Ali

6

1 reference

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15 January 2020

Alastair J Munro

7

1 reference

Europe PubMed Central

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15 January 2020

Lee Baker

8

1 reference

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15 January 2020

Alastair M Thompson

11

1 reference

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15 January 2020

language of work or name

0 references

publication date

1 October 2008

1 reference

Europe PubMed Central

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15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828900%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

8

1 reference

Europe PubMed Central

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15 January 2020

281

1 reference

Europe PubMed Central

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15 January 2020

https://scigraph.springernature.com/pub.10.1186/1471-2407-8-281

0 references

A polymorphism in HDM2 (SNP309) associates with early onset in superficial tumors, TP53 mutations, and poor outcome in invasive bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-SNP309 colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Detection of functional single-nucleotide polymorphisms that affect apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

The MDM2 promoter polymorphism SNP309T-->G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Haploview: analysis and visualization of LD and haplotype maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Best Practice No 176: Updated recommendations for HER2 testing in the UK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

The p53-Mdm2 module and the ubiquitin system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Strategies for manipulating the p53 pathway in the treatment of human cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Induction of Mdm2 and enhancement of cell survival by bFGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

A functional p53-responsive intronic promoter is contained within the human mdm2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

21 June 2018

MDM2 309T>G polymorphism and risk of lung cancer in a Korean population.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

No association between the MDM2 -309 T/G promoter polymorphism and breast cancer in African-Americans or Whites

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

MDM2 SNP309 and cancer risk: a combined analysis.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

No association of the MDM2 SNP309 polymorphism with risk of breast or ovarian cancer.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

The p53 Arg72Pro and MDM2 -309 polymorphisms and risk of breast cancer in the nurses' health studies.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

MDM2 SNP309 accelerates familial breast carcinogenesis independently of estrogen signaling.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

The single nucleotide polymorphism IVS1+309 in mouse double minute 2 does not affect risk of familial breast cancer.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

MDM2 SNP309 and SNP354 are not associated with lung cancer risk.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

Single nucleotide polymorphism 309 affects murin-double-minute 2 protein expression but not glioma tumorigenesis.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

Lack of association between the MDM2-SNP309 polymorphism and breast cancer risk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576335

31 October 2018

p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-281

21 January 2018

Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDM2 promoter SNP309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in Chinese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of polymorphism in MDM-2 and p53 genes with breast cancer risk in Indian women

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Nottingham prognostic index in primary breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of breast cancer outcome with status of p53 and MDM2 SNP309

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDM2 gene amplification in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53 and breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18828900

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-8-281

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828900%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828900%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18828900%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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