(Q42490237)

1 November 2017

title

Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency (English)

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1 November 2017

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Lynch CJ

1

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1 November 2017

Milner J

series ordinal

2

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1 November 2017

language of work or name

English

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publication date

30 January 2006

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1 November 2017

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1 November 2017

volume

25

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1 November 2017

issue

24

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1 November 2017

page(s)

3463-3470

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209387

1 November 2017

exact match

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cites work

Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect

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7 January 2021

Post-translational modification of p53 in tumorigenesis

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7 January 2021

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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7 January 2021

A possible screening test for inherited p53-related defects based on the apoptotic response of peripheral blood lymphocytes to DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Accommodating haploinsufficient tumor suppressor genes in Knudson's model

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

The tumor suppressor p53 regulates its own transcription

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7 January 2021

Mechanisms of translational control by the 3' UTR in development and differentiation

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7 January 2021

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

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7 January 2021

p53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53.

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7 January 2021

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

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7 January 2021

Functions of the MDM2 oncoprotein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

A translation repressor element resides in the 3' untranslated region of human p53 mRNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

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7 January 2021

The interaction between FOXO and SIRT1: tipping the balance towards survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

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7 January 2021

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

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7 January 2021

p53: 25 years after its discovery

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7 January 2021

p53 mutations in human cancers

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7 January 2021

Metabolic radiolabeling: experimental tool or Trojan horse? (35)S-Methionine induces DNA fragmentation and p53-dependent ROS production.

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7 January 2021

Could p53 be a target for therapeutic suppression?

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7 January 2021

Cellular UV damage responses--functions of tumor suppressor p53.

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7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

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7 January 2021

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

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7 January 2021

Metabolic labeling of human cells with tritiated nucleosides results in activation of the ATM-dependent p53 signaling pathway and acceleration of DNA repair

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Disrupting TP53 in mouse models of human cancers

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Tumor suppressor genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

p53 mutation heterogeneity in cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Li-Fraumeni syndrome--a molecular and clinical review

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Surfing the p53 network

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Activation of the p53 tumor suppressor protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Cell cycle arrest defect in Li-Fraumeni Syndrome: a mechanism of cancer predisposition?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Cell death and cell-cycle arrest induced by incorporation of [3H]thymidine into human haemopoietic cell lines

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209387

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209387

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Dimensions Publication ID

1 November 2017

1020863712

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Fatcat ID

release_qdoq622vxvd4tb54bqmsd5p32m

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Fatcat

https://api.fatcat.wiki/v0/release/qdoq622vxvd4tb54bqmsd5p32m

24 November 2022

mapped directly with Wikidata item

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