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The p53-Mdm2 module and the ubiquitin system.
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Europe PubMed Central
PubMed publication ID
12507556
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
review article
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Europe PubMed Central
title
The p53-Mdm2 module and the ubiquitin system
(English)
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Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
author
Dan Michael
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
author name string
Moshe Oren
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2
1 reference
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Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
publication date
1 February 2003
1 reference
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Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
published in
Seminars in Cancer Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
volume
13
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
page(s)
49-58
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
cites work
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Surfing the p53 network
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7 January 2021
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The ins and outs of p53
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7 January 2021
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Regulation of p53 function
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7 January 2021
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p53: death star
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7 January 2021
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Virus-mediated killing of cells that lack p53 activity
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7 January 2021
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A model for tumor suppression using H-1 parvovirus
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7 January 2021
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mdm2 expression is induced by wild type p53 activity
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
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The p53-mdm-2 autoregulatory feedback loop
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
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inferred from DOI database lookup
MDM2--master regulator of the p53 tumor suppressor protein
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2: life without p53.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a cryptic nucleolar-localization signal in MDM2
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
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inferred from DOI database lookup
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
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Crossref
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7 January 2021
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A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The loss of mdm2 induces p53-mediated apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
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inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Mdm2-directed degradation by the C terminus of p53.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
C-terminal ubiquitination of p53 contributes to nuclear export
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition of the polyubiquitin proteolytic signal
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin-mediated proteolysis: biological regulation via destruction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The complexity of p53 modulation: emerging patterns from divergent signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage induces phosphorylation of the amino terminus of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 function and stability by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of sequence elements involved in p53 stability regulation reveals cell type dependence for p53 degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 gene is induced in response to UV light in a p53-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress signals utilize multiple pathways to stabilize p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 Activation by nitric oxide involves down-regulation of Mdm2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ARF/p53 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleolar Arf sequesters Mdm2 and activates p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyoma virus disrupts ARF signaling to p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 and MDMX can interact differently with ARF and members of the p53 family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RB regulates the stability and the apoptotic function of p53 via MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Abl neutralizes the inhibitory effect of Mdm2 on p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The contribution of the acidic domain of MDM2 to p53 and MDM2 stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 mutant defective in binding p300 promotes ubiquitination but not degradation of p53: evidence for the role of p300 in integrating ubiquitination and proteolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical association of ubiquitin ligases and the 26S proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of murine double minute clone 2 (MDM2) protein at serine-267 by protein kinase CK2 in vitro and in cultured cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MDM2 RING-finger domain is required to promote p53 nuclear export
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2-dependent ubiquitination of nuclear and cytoplasmic P53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear degradation of p53 occurs during down-regulation of the p53 response after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolysis by calpains: a possible contribution to degradation of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the involvement of calpains in the degradation of the tumor suppressor protein p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEKK1/JNK signaling stabilizes and activates p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK targets p53 ubiquitination and degradation in nonstressed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900099-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1044-579X(02)00099-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
PubMed publication ID
12507556
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12507556
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12507556%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
ResearchGate publication ID
10967890
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