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Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.
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1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author
Susana Llanos
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
P A Clark
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
J Rowe
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
G Peters
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 May 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Nature Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
445-452
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/35074506
0 references
cites work
Tumor surveillance via the ARF-p53 pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The INK4A/ARF locus and its two gene products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for E2F proteins in cell growth control and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleolar Arf sequesters Mdm2 and activates p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 functions as a cell cycle control protein in osteosarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p19ARF prevents G1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methods used to study structure and function of the nucleolus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggresomes: a cellular response to misfolded proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a cryptic nucleolar-localization signal in MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35074506
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed ID
11331871
1 reference
stated in
Europe PubMed Central
PubMed ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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