(Q73673966)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

The loss of mdm2 induces p53-mediated apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

S de Rozieres

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

R Maya

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

M Oren

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

G Lozano

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 March 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

1691-1697

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10763826%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203468

5 November 2019

exact match

0 references

cites work

Suppression of human colorectal carcinoma cell growth by wild-type p53

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7 January 2021

mdm2 expression is induced by wild type p53 activity

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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7 January 2021

TP53 tumor suppressor gene: a model for investigating human mutagenesis

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7 January 2021

Genetic mechanisms of tumor suppression by the human p53 gene

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7 January 2021

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

Cyclin E restores p53 activity in contact-inhibited cells

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7 January 2021

p53 functions as a cell cycle control protein in osteosarcomas

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

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7 January 2021

Presence of a potent transcription activating sequence in the p53 protein

1 reference

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7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

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7 January 2021

Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

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7 January 2021

Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein

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7 January 2021

p53 in growth control and neoplasia

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7 January 2021

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7 January 2021

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

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7 January 2021

p53 mutations in human cancers

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7 January 2021

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

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7 January 2021

Tumor spectrum analysis in p53-mutant mice

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7 January 2021

Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells

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7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Identification of p53 as a sequence-specific DNA-binding protein

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

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7 January 2021

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

1 reference

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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7 January 2021

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7 January 2021

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

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7 January 2021

Tumor suppressor genes

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7 January 2021

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

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7 January 2021

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

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7 January 2021

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

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7 January 2021

The MDM2 gene amplification database

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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7 January 2021

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

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7 January 2021

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

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7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

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7 January 2021

Mdm2: keeping p53 under control

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7 January 2021

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

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7 January 2021

Analysis of p53 mutants for transcriptional activity

1 reference

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7 January 2021

Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells

1 reference

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

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7 January 2021

Estrogen receptor-negative breast cancer cells transfected with the estrogen receptor exhibit increased RAR alpha gene expression and sensitivity to growth inhibition by retinoic acid

1 reference

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7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

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7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

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7 January 2021

p53-mediated cell death: relationship to cell cycle control

1 reference

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7 January 2021