(Q33373673)

English

A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 July 2017

A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Martin Hrabě de Angelis

13

object named as

Martin Hrabe de Angelis

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object named as

Karen B Avraham

15

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object named as

Nir Ben-Tal

11

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14

object named as

Karen P Steel

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

1 reference

ORCID Public Data File 2021

12

object named as

H Lee Sweeney

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Europe PubMed Central

PubMed publication ID

26 July 2017

author name string

Ronna Hertzano

1

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Europe PubMed Central

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26 July 2017

Ella Shalit

2

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Europe PubMed Central

PubMed publication ID

26 July 2017

Agnieszka K Rzadzinska

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Amiel A Dror

4

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Lin Song

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Uri Ron

6

1 reference

Europe PubMed Central

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26 July 2017

Joshua T Tan

7

1 reference

Europe PubMed Central

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26 July 2017

Alina Starovolsky Shitrit

8

1 reference

Europe PubMed Central

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26 July 2017

Helmut Fuchs

9

1 reference

Europe PubMed Central

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26 July 2017

Tama Hasson

10

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Europe PubMed Central

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26 July 2017

publication date

3 October 2008

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Europe PubMed Central

PubMed publication ID

26 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

e1000207

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

copyright license

Creative Commons Attribution 4.0 International

3 October 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Mouse models to study inner ear development and hereditary hearing loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

How myosin VI coordinates its heads during processive movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

What can myosin VI do in cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Nuclear myosin VI enhances RNA polymerase II-dependent transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

The structure of the myosin VI motor reveals the mechanism of directionality reversal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

The Universal Protein Resource (UniProt)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Three myosin V structures delineate essential features of chemo-mechanical transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Regulation of myosin-VI targeting to endocytic compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

MUSCLE: a multiple sequence alignment method with reduced time and space complexity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Uncoated endocytic vesicles require the unconventional myosin, Myo6, for rapid transport through actin barriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Mouse models for deafness: lessons for the human inner ear and hearing loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Mutations of MYO6 are associated with recessive deafness, DFNB37

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

A novel stereocilia defect in sensory hair cells of the deaf mouse mutant Tasmanian devil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

DOC-2/DAB2 is the binding partner of myosin VI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Arp2/3 complex: advances on the inner workings of a molecular machine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Myosin VI, a new force in clathrin mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

ConSurf: an algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Class VI unconventional myosin is required for spermatogenesis in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Role of myosin VI in the differentiation of cochlear hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Myosin VI is an actin-based motor that moves backwards

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Profile hidden Markov models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Unconventional myosins in inner-ear sensory epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

ARPE-19, a human retinal pigment epithelial cell line with differentiated properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Porcine myosin-VI: characterization of a new mammalian unconventional myosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

An unconventional myosin heavy chain gene from Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

A technique for preparation of cochlear specimens for assessment with the scanning electron microscope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2543112

21 June 2018

Myosin VI is required for asymmetric segregation of cellular components during C. elegans spermatogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Novel association of hypertrophic cardiomyopathy, sensorineural deafness, and a mutation in unconventional myosin VI (MYO6).

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Tailchaser (Tlc): a new mouse mutation affecting hair bundle differentiation and hair cell survival.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Rate4Site: an algorithmic tool for the identification of functional regions in proteins by surface mapping of evolutionary determinants within their homologues

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Development and properties of stereociliary link types in hair cells of the mouse cochlea

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

A role for myosin VI in actin dynamics at sites of membrane remodeling during Drosophila spermatogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Dynamic compartmentalization of protein tyrosine phosphatase receptor Q at the proximal end of stereocilia: implication of myosin VI-based transport

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

The mechanism of myosin VI translocation and its load-induced anchoring

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Calcium functionally uncouples the heads of myosin VI.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

ConSeq: the identification of functionally and structurally important residues in protein sequences

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Kinetic mechanism and regulation of myosin VI.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000207

21 January 2018

Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18833301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subdomain folding of the coiled coil leucine zipper from the bZIP transcriptional activator GCN4

1 reference

https://pubmed.ncbi.nlm.nih.gov/18833301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic tuning of myosin via a flexible loop adjacent to the nucleotide binding pocket

1 reference

https://pubmed.ncbi.nlm.nih.gov/18833301

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1000207

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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