(Q33377922)

26 July 2017

title

Directed enzyme evolution via small and effective neutral drift libraries (English)

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26 July 2017

Rinkoo D Gupta

1

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author name string

Dan S Tawfik

series ordinal

2

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26 July 2017

publication date

19 October 2008

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26 July 2017

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26 July 2017

volume

5

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26 July 2017

issue

11

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26 July 2017

page(s)

939-942

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Intense neutral drifts yield robust and evolvable consensus proteins

26 July 2017

cites work

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https://api.crossref.org/works/10.1038%2FNMETH.1262

Evolution favors protein mutational robustness in sufficiently large populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Latent evolutionary potentials under the neutral mutational drift of an enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Genetic screens and directed evolution for protein solubility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

A second-generation system for unbiased reading frame selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Molecular diversity in engineered protein libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

How protein stability and new functions trade off

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

FACS-optimized mutants of the green fluorescent protein (GFP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Engineering and characterization of a superfolder green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

High-throughput screening of enzyme libraries: thiolactonases evolved by fluorescence-activated sorting of single cells in emulsion compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

Ohno's model revisited: measuring the frequency of potentially adaptive mutations under various mutational drifts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNMETH.1262

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NMETH.1262

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Dimensions Publication ID

26 July 2017

1040562139

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