(Q33384102)

26 July 2017

title

A phase I study of extended dosing with lomeguatrib with temozolomide in patients with advanced melanoma (English)

1 reference

26 July 2017

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J Beith

7

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author name string

R F Kefford

1

1 reference

26 July 2017

N P B Thomas

2

1 reference

26 July 2017

P G Corrie

3

1 reference

26 July 2017

C Palmer

4

1 reference

26 July 2017

E Abdi

5

1 reference

26 July 2017

D Kotasek

6

1 reference

26 July 2017

M Ranson

8

1 reference

26 July 2017

P Mortimer

9

1 reference

26 July 2017

A J Watson

10

1 reference

26 July 2017

G P Margison

11

1 reference

26 July 2017

M R Middleton

12

1 reference

26 July 2017

language of work or name

English

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publication date

31 March 2009

1 reference

British Journal of Cancer

26 July 2017

published in

1 reference

26 July 2017

volume

100

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26 July 2017

issue

8

1 reference

26 July 2017

page(s)

1245-1249

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MGMT gene silencing and benefit from temozolomide in glioblastoma

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Improvement of chemotherapy efficacy by inactivation of a DNA-repair pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

O6-alkylguanine-DNA alkyltransferase assay.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Tumor doubling time: a selection factor for pulmonary resection of metastatic melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

O6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

DNA damage tolerance, mismatch repair and genome instability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Chinese hamster cells harbouring the Escherichia coli O6-alkylguanine alkyltransferase gene are less susceptible to sister chromatid exchange induction and chromosome damage by methylating agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

O6-methylguanine-DNA methyltransferase activity in human tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Association between growth stimulation by phenobarbital and expression of cytochromes P450 1A1, 1A2, 2B1/2 and 3A1 in hepatic hyperplastic nodules in male F344 rats

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605016

Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605016

Analysis of O(6)-methylguanine-DNA methyltransferase in melanoma tumours in patients treated with dacarbazine-based chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605016

Delayed DNA maturation, a possible cause of the elevated sister-chromatid exchange in Bloom's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605016

Lomeguatrib, a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase: phase I safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605016

O6-benzylguanine-mediated enhancement of chemotherapy.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676549

Randomized Trial of the Combination of Lomeguatrib and Temozolomide Compared With Temozolomide Alone in Chemotherapy Naive Patients With Metastatic Cutaneous Melanoma

31 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605016

Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19367282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6605016

1 reference

Dimensions Publication ID

26 July 2017

0 references

1 reference

26 July 2017

1 reference