(Q33408394)

26 July 2017

title

DNA instability in replicating Huntington's disease lymphoblasts (English)

1 reference

26 July 2017

0 references

Vittorio Maglione

2

0 references

Milena Cannella

object named as

Milena Cannella

1

0 references

Guo-Min Li

object named as

Guo-Min Li

6

0 references

Ferdinando Squitieri

object named as

Ferdinando Squitieri

7

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author name string

Tiziana Martino

3

1 reference

26 July 2017

Giuseppe Ragona

4

1 reference

26 July 2017

Luigi Frati

5

1 reference

26 July 2017

publication date

11 February 2009

1 reference

26 July 2017

1 reference

26 July 2017

volume

10

1 reference

26 July 2017

page(s)

11

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2350-10-11

26 July 2017

exact match

0 references

cites work

DNA instability in postmitotic neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

A universal mechanism ties genotype to phenotype in trinucleotide diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Chemical modifiers of unstable expanded simple sequence repeats: what goes up, could come down

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Chemotherapeutic deletion of CTG repeats in lymphoblast cells from DM1 patients

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

New Huntington disease mutation arising from a paternal CAG34 allele showing somatic length variation in serially passaged lymphoblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Chemically induced increases and decreases in the rate of expansion of a CAG*CTG triplet repeat

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Single cell analysis of CAG repeat in brains of dentatorubral-pallidoluysian atrophy (DRPLA).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Differential somatic CAG repeat instability in variable brain cell lineage in dentatorubral pallidoluysian atrophy (DRPLA): a laser-captured microdissection (LCM)-based analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Analysis of (CAG)n size heterogeneity in somatic and sperm cell DNA from intermediate and expanded Huntington disease gene carriers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Instability of the expanded (CTG)n repeats in the myotonin protein kinase gene in cultured lymphoblastoid cell lines from patients with myotonic dystrophy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: cellular population-dependent dynamics of mitotic instability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Increased instability of intermediate alleles in families with sporadic Huntington disease compared to similar sized intermediate alleles in the general population

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Mutation of human short tandem repeats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

DNA haplotype analysis of Huntington disease reveals clues to the origins and mechanisms of CAG expansion and reasons for geographic variations of prevalence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645380

Mutational bias provides a model for the evolution of Huntington's disease and predicts a general increase in disease prevalence.

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

The gender effect in juvenile Huntington disease patients of Italian origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Single sperm analysis of the trinucleotide repeats in the Huntington's disease gene: quantification of the mutation frequency spectrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Inherited CAG.CTG allele length is a major modifier of somatic mutation length variability in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Microsatellites show mutational bias and heterozygote instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Instability of the CAG repeat in immortalized fibroblast cell cultures from Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-10-11

Somatic sequence variation at the Friedreich ataxia locus includes complete contraction of the expanded GAA triplet repeat, significant length variation in serially passaged lymphoblasts and enhanced mutagenesis in the flanking sequence

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19210789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Various inhibitors of DNA topoisomerases diminish repair-specific DNA incision in UV-irradiated human fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19210789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19210789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2350-10-11

1 reference

26 July 2017

1 reference

26 July 2017

1 reference