(Q40721588)

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10 November 2019

title

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines (English)

1 reference

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10 November 2019

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4

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10 November 2019

James R Burke

5

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10 November 2019

J. Timothy Greenamyre

7

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10 November 2019

3

Blair R Leavitt

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10 November 2019

Claire-Anne Gutekunst

2

object named as

Claire-Anne Gutekunst

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10 November 2019

author name string

Alexander V Panov

1

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10 November 2019

Warren J Strittmatter

6

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10 November 2019

language of work or name

English

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publication date

1 August 2002

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10 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12089530%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

5

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10 November 2019

page(s)

731-736

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10 November 2019

issue

8

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https://scigraph.springernature.com/pub.10.1038/nn884

10 November 2019

exact match

0 references

cites work

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

7 January 2021

Beyond the Qs in the polyglutamine diseases

1 reference

7 January 2021

Wild-type huntingtin protects from apoptosis upstream of caspase-3.

1 reference

7 January 2021

Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo

1 reference

7 January 2021

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

7 January 2021

Loss of normal huntingtin function: new developments in Huntington's disease research

1 reference

7 January 2021

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

7 January 2021

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

7 January 2021

Huntingtin interacts with a family of WW domain proteins

1 reference

7 January 2021

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

1 reference

7 January 2021

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

7 January 2021

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

1 reference

7 January 2021

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

1 reference

7 January 2021

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

7 January 2021

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

7 January 2021

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

1 reference

7 January 2021

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

1 reference

7 January 2021

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

7 January 2021

Bioenergetics and glutamate excitotoxicity

1 reference

7 January 2021

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

1 reference

7 January 2021

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

1 reference

7 January 2021

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

7 January 2021

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

1 reference

7 January 2021

The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human.

1 reference

7 January 2021

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

1 reference

7 January 2021

Poly-L-glutamine forms cation channels: relevance to the pathogenesis of the polyglutamine diseases

1 reference

7 January 2021

Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.

1 reference

7 January 2021

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

1 reference

7 January 2021

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

7 January 2021

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.

1 reference

7 January 2021

Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

1 reference

7 January 2021

Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation

1 reference

7 January 2021

Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells

1 reference

7 January 2021

Identifiers

DOI

10.1038/NN884

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12089530%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 November 2019

0 references

1 reference