(Q33431139)

26 July 2017

title

Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins (English)

1 reference

26 July 2017

Jun Wei

1

1 reference

26 July 2017

Shinichi Kitada

2

1 reference

26 July 2017

Michele F Rega

3

1 reference

26 July 2017

Aras Emdadi

4

1 reference

26 July 2017

Hongbin Yuan

5

1 reference

26 July 2017

Jason Cellitti

6

1 reference

26 July 2017

John L Stebbins

7

1 reference

26 July 2017

Dayong Zhai

8

1 reference

26 July 2017

Jiazhi Sun

9

1 reference

26 July 2017

Li Yang

10

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26 July 2017

Russell Dahl

11

1 reference

26 July 2017

Ziming Zhang

12

1 reference

26 July 2017

Bainan Wu

13

1 reference

26 July 2017

Si Wang

14

1 reference

26 July 2017

Tyler A Reed

15

1 reference

26 July 2017

Hong-Gang Wang

16

1 reference

26 July 2017

Nicholas Lawrence

17

1 reference

26 July 2017

Said Sebti

18

1 reference

26 July 2017

John C Reed

19

1 reference

26 July 2017

Maurizio Pellecchia

20

1 reference

26 July 2017

publication date

1 April 2009

1 reference

Molecular Cancer Therapeutics

26 July 2017

published in

1 reference

26 July 2017

volume

8

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26 July 2017

issue

4

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26 July 2017

page(s)

904-913

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Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Killing cancer cells by flipping the Bcl-2/Bax switch.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Apoptosis-based therapies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Apoptosis: a link between cancer genetics and chemotherapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Structure-activity studies on gossypol in tumor cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Dysregulation of apoptosis in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

BCL-2 family members and the mitochondria in apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

The Bcl-2 protein family: arbiters of cell survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Bcl-2 family proteins: strategies for overcoming chemoresistance in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Development and validation of a genetic algorithm for flexible docking

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Differential effects of Bcl-2 on T and B cells in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

21 June 2018

Bcl-2 family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Molecular biology of chronic lymphocytic leukemia: implications for therapy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2750823

Quantitative determination of apogossypol, a pro-apoptotic analog of gossypol, in mouse plasma using LC/MS/MS

31 October 2018

1 reference

12 December 2020

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells

1 reference

12 December 2020

Texture mapping: a new tool for molecular graphics

1 reference

12 December 2020

Cell Death in Development

1 reference

12 December 2020

10.1158/1535-7163.MCT-08-1050

Identifiers

DOI

1 reference

release_6igcstxpqzaaxnvuvv43g3poby

26 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6igcstxpqzaaxnvuvv43g3poby

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2750823

1 reference

26 July 2017

1 reference