(Q33431379)

26 July 2017

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title

Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis (English)

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26 July 2017

1

Jared T Shaw

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26 July 2017

publication date

1 January 2009

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26 July 2017

published in

Natural Product Reports

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26 July 2017

volume

26

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26 July 2017

issue

1

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26 July 2017

page(s)

11-26

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Integrating high-content screening and ligand-target prediction to identify mechanism of action

26 July 2017

cites work

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Design and implementation of cell-based assays to model human disease.

21 January 2018

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Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics.

21 January 2018

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Small molecules: the missing link in the central dogma

21 January 2018

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Multidimensional drug profiling by automated microscopy.

21 January 2018

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Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton

21 January 2018

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Natural products as sources of new drugs over the last 25 years

21 January 2018

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Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries

21 January 2018

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Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries

21 January 2018

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Natural product-like libraries based on non-aromatic, polycyclic motifs

21 January 2018

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Natural products and combinatorial chemistry: back to the future

21 January 2018

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Libraries from natural product-like scaffolds

21 January 2018

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A planning strategy for diversity-oriented synthesis

21 January 2018

1 reference

Intramolecular Schmidt Reaction: Applications in Natural Product Synthesis

21 January 2018

1 reference

Synthesis and structural analysis of 2-quinuclidonium tetrafluoroborate

21 January 2018

1 reference

Asymmetric Total Synthesis of Dendrobatid Alkaloids: Preparation of Indolizidine 251F and Its 3-Desmethyl Analogue Using an Intramolecular Schmidt Reaction Strategy

21 January 2018

1 reference

Asymmetric total synthesis of dendrobatid alkaloid 251F.

21 January 2018

1 reference

Revisiting a classic approach to the Aspidosperma alkaloids: an intramolecular Schmidt reaction mediated synthesis of (+)-aspidospermidine.

21 January 2018

1 reference

Synthesis and conformational studies of dipeptides constrained by disubstituted 3-(aminoethoxy)propionic acid linkers

21 January 2018

1 reference

Three-component synthesis of 1,4-diazepin-5-ones and the construction of gamma-turn-like peptidomimetic libraries

21 January 2018

1 reference

Nucleophilic addition to iminium ethers in the preparation of functionalized N-alkyl heterocycles

21 January 2018

1 reference

Explorations of stemona alkaloid-inspired analogues: skeletal modification and functional group diversification

21 January 2018

1 reference

Total synthesis of (-)-martinellic acid via radical addition-cyclization-elimination reaction.

21 January 2018

1 reference

Multi-component coupling reactions: synthesis of a guanidine containing analog of the hexahydropyrrolo[3,2-c]quinoline alkaloid martinelline

21 January 2018

1 reference

Computational Insight Concerning Catalytic Decision Points of the Transition Metal Catalyzed [2 + 2 + 1] Cyclocarbonylation Reaction of Allenes

21 January 2018

1 reference

Discovery and development of sesquiterpenoid derived hydroxymethylacylfulvene: a new anticancer drug

21 January 2018

1 reference

Synthesis and biological activity of enantiomers of antitumor irofulven

21 January 2018

1 reference

Guanacastepene, a Fungal-Derived Diterpene Antibiotic with a New Carbon Skeleton

21 January 2018

1 reference

Total Synthesis of (−)-Heptemerone B and (−)-Guanacastepene E

21 January 2018

1 reference

Enantioselective total synthesis of guanacastepene N using an uncommon 7-endo Heck cyclization as a pivotal step

21 January 2018

1 reference

Short synthesis of skeletally and stereochemically diverse small molecules by coupling petasis condensation reactions to cyclization reactions

21 January 2018

1 reference

Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library

21 January 2018

1 reference

Rhodium(I)-catalyzed allenic carbocyclization reaction affording delta- and epsilon-lactams

21 January 2018

1 reference

Skeletal diversity via a branched pathway: efficient synthesis of 29 400 discrete, polycyclic compounds and their arraying into stock solutions.

21 January 2018

1 reference

Total synthesis of herboxidiene/GEX 1A.

21 January 2018

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Total synthesis of bistramide A.

21 January 2018

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Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

21 January 2018

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A sequential two-component etherification/oxa-conjugate addition reaction: asymmetric synthesis of (+)-leucascandrolide A macrolactone.

21 January 2018

1 reference

Total synthesis of leucascandrolide a: a new application of the Mukaiyama aldol-Prins reaction

21 January 2018

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Formal synthesis of leucascandrolide A.

21 January 2018

1 reference

Advances in the total synthesis of biologically important marine macrolides

21 January 2018

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Total synthesis and structural revision of the marine macrolide neopeltolide

21 January 2018

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Synthesis of a library of complex macrodiolides employing cyclodimerization of hydroxy esters

21 January 2018

1 reference

Stereochemical diversity through cyclodimerization: synthesis of polyketide-like macrodiolides

21 January 2018

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Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets

21 January 2018

1 reference

Stereochemical and skeletal diversity employing pipecolate ester scaffolds

21 January 2018

1 reference

Total Synthesis of the Quinone Epoxide Dimer (+)-Torreyanic Acid: Application of a Biomimetic Oxidation/Electrocyclization/Diels−Alder Dimerization Cascade1

21 January 2018

1 reference

Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, blocks activation of transcription factor nuclear factor kappaB by inhibiting the inhibitor of kappaB kinase.

21 January 2018

1 reference

Angiogenesis inhibitor epoxyquinol a: total synthesis and inhibition of transcription factor NF-kappaB.

21 January 2018

1 reference

Synthesis of epoxyquinol A and related molecules: probing chemical reactivity of epoxyquinol dimers and 2H-pyran precursors

21 January 2018

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Total synthesis of epoxyquinols A, B, and C and epoxytwinol A and the reactivity of a 2H-pyran derivative as the diene component in the Diels-Alder reaction

21 January 2018

1 reference

Synthesis of the epoxyquinol dimer RKB-3564 D: utilization of an alkoxysilanol to promote [4 + 4] dimerization

21 January 2018

1 reference

Total synthesis of the ubiquitin-activating enzyme inhibitor (+)-panepophenanthrin

21 January 2018

1 reference

Total syntheses of hexacyclinol, 5-epi-hexacyclinol, and desoxohexacyclinol unveil an antimalarial prodrug motif

21 January 2018

1 reference

Predicting NMR spectra by computational methods: structure revision of hexacyclinol

21 January 2018

1 reference

Applying computer-assisted structure elucidation algorithms for the purpose of structure validation: revisiting the NMR assignments of hexacyclinol

21 January 2018

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Total synthesis and structure assignment of (+)-hexacyclinol.

21 January 2018

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Stereocontrolled synthesis of a complex library via elaboration of angular epoxyquinol scaffolds

21 January 2018

1 reference

Identification of Novel Epoxide Inhibitors of Hepatitis C Virus Replication Using a High-Throughput Screen

21 January 2018

1 reference

Cyclic anhydrides in formal cycloadditions and multicomponent reactions.

21 January 2018

1 reference

New approach for preparation of 2,3,7-trisubstituted 3,4-dihydroisoquinolinone libraries on solid phase

21 January 2018

1 reference

A general and efficient copper catalyst for the amidation of aryl halides

21 January 2018

1 reference

A structurally diverse library of polycyclic lactams resulting from systematic placement of proximal functional groups

21 January 2018

1 reference

Design and synthesis of a 3,4-dehydroproline amide discovery library

21 January 2018

1 reference

Diverging Rh(I)-catalyzed carbocylization strategy to prepare a library of unique cyclic ethers

21 January 2018

1 reference

Skeletal and Appendage Diversity as Design Elements in the Synthesis of a Discovery Library of Nonaromatic Polycyclic 5-Iminooxazolidin-2-ones, Hydantoins, and Acylureas

21 January 2018

1 reference

Chapter 26 The Molecular Libraries Screening Center Network (MLSCN): Identifying Chemical Probes of Biological Systems

21 January 2018

1 reference

Charting Biological and Chemical Space: PSSC and SCONP as Guiding Principles for the Development of Compound Collections Based on Natural Product Scaffolds

21 January 2018

1 reference

Total Synthesis of (+)-Neopeltolide

21 January 2018

1 reference

The proof is in the product

21 January 2018

1 reference

Leucascandrolide A, a New Type of Macrolide: The first powerfully bioactive metabolite of calcareous sponges (Leucascandra caveolata, a new genus from the coral sea)

21 January 2018

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/HLCA.19960790107

Hexacylinol, a New Antiproliferative Metabolite of Panus rudis HKI 0254.

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.55.814

Leucascandrolide B, a New 16-Membered, Extensively Methyl-Branched Polyoxygenated Macrolide from the Calcareous SpongeLeucascandra caveolata from Northeastern Waters of New Caledonia

12 April 2024

1 reference

11 May 2024

https://opencitations.net/index/api/v1/citations/10.1002/(SICI)1522-2675(19990310)82:3%3C347::AID-HLCA347%3E3.0.CO;2-9

Identifiers

DOI

10.1039/B814468K

1 reference

release_zxndpmeh6nbpjibsp4wc4r4mt4

26 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zxndpmeh6nbpjibsp4wc4r4mt4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference