(Q33471458)

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Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression

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scholarly article

1 reference

Europe PubMed Central

27 July 2017

Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression (English)

1 reference

Europe PubMed Central

27 July 2017

object named as

Robert Simms

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Robert Lafyatis

object named as

Robert Lafyatis

10

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author name string

Timothy R D J Radstake

1

1 reference

Europe PubMed Central

27 July 2017

Lenny van Bon

2

1 reference

Europe PubMed Central

27 July 2017

Jasper Broen

3

1 reference

Europe PubMed Central

27 July 2017

Mark Wenink

4

1 reference

Europe PubMed Central

27 July 2017

Kim Santegoets

5

1 reference

Europe PubMed Central

27 July 2017

Yanhui Deng

6

1 reference

Europe PubMed Central

27 July 2017

Anila Hussaini

7

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Europe PubMed Central

27 July 2017

William W Cruikshank

9

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Europe PubMed Central

27 July 2017

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publication date

22 June 2009

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

4

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Europe PubMed Central

27 July 2017

6

1 reference

Europe PubMed Central

27 July 2017

e5981

1 reference

Europe PubMed Central

27 July 2017

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Creative Commons Attribution 4.0 International

22 June 2009

1 reference

April 2022 Public Data File from Crossref

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0 references

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

1 reference

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21 June 2018

Role of regulatory T cells for the treatment of type 1 diabetes mellitus

1 reference

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21 June 2018

Special regulatory T cell review: How I became a T suppressor/regulatory cell maven

1 reference

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21 June 2018

Development, cytokine profile and function of human interleukin 17-producing helper T cells

1 reference

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21 June 2018

Phenotypic and functional features of human Th17 cells

1 reference

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21 June 2018

Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

1 reference

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21 June 2018

FOXP3: of mice and men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Early T cell activation in the skin from patients with systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo

1 reference

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21 June 2018

Failure of CD25+ T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Mechanisms of suppression by suppressor T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Alterations of mononuclear inflammatory cells, CD4/CD8+ T cells, interleukin 1beta, and tumour necrosis factor alpha in the bronchoalveolar lavage fluid, peripheral blood, and skin of patients with systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Enhanced antitumor immunity in mice deficient in CD69.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Natural versus adaptive regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Regulatory T cells in transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Regulatory T cells under scrutiny

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

CD4(+) regulatory T cells in autoimmunity and allergy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Suppressor T cells--they're back and critical for regulation of autoimmunity!

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: implications for autoimmunity and tumor immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Criteria for the classification of early systemic sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Expression of CD69 antigen on synovial fluid T cells in patients with rheumatoid arthritis and other chronic synovitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Increase in activated T cells and reduction in suppressor inducer T cells in systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

21 June 2018

Reduced CD4+,CD25- T cell sensitivity to the suppressive function of CD4+,CD25high,CD127 -/low regulatory T cells in patients with active systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Altered frequency and migration capacity of CD4+CD25+ regulatory T cells in systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Foxp3 expression in CD4+ T cells of patients with systemic lupus erythematosus: a comparative phenotypic analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Targeting activated T cells: successful use of anti-CD25 monoclonal antibody basiliximab in a patient with systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Evaluation of topoisomerase-1-specific CD8+ T-cell response in systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Dressed neurons: modeling neural-glial interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

A subset of CD4+ T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2695559

31 October 2018

Increased interleukin-17 production in patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of intestinal inflammation by regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal expression of intracellular cytokines and chemokine receptors in peripheral blood T lymphocytes from patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and regulation of CD69 expression on rheumatoid arthritis synovial fluid T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced circulating natural killer T cells and gamma/delta T cells in patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GITR-GITRL interaction: co-stimulation or contrasuppression of regulatory activity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinflammatory mediator–induced reversal of CD4+,CD25+ regulatory T cell–mediated suppression in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells expressing allograft inflammatory factor 1 display increased chemotaxis and induce a profibrotic phenotype in normal fibroblasts in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased serum interleukin 23 in patients with systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19543397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0005981

1 reference

Europe PubMed Central

27 July 2017

2009PLoSO...4.5981R

0 references

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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