(Q35092531)

6 August 2017

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title

Regulatory T cells under scrutiny (English)

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6 August 2017

1

Jean-François Bach

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publication date

1 March 2003

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Nature Reviews Immunology

6 August 2017

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6 August 2017

3

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6 August 2017

189-198

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6 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nri1026

6 August 2017

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cites work

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Healthy monozygous twins do not recognize identical T cell epitopes on the myelin basic protein autoantigen

31 March 2020

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High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.

31 March 2020

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Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

31 March 2020

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Effect of Thymectomy in Adult Mice on Immunological Responsiveness

31 March 2020

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Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

31 March 2020

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

31 March 2020

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Acceleration of the onset of diabetes in NOD mice by thymectomy at weaning

31 March 2020

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Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential

31 March 2020

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OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset

31 March 2020

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Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

31 March 2020

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High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

31 March 2020

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Beta cell apoptosis in T cell-mediated autoimmune diabetes

31 March 2020

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Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes

31 March 2020

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Regulation of naïve and memory T-cell homeostasis

31 March 2020

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Maintaining the norm: T-cell homeostasis

31 March 2020

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T cell homeostasis and systemic autoimmunity

31 March 2020

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T cell regulation as a side effect of homeostasis and competition

31 March 2020

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Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

31 March 2020

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CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

31 March 2020

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The effect of infections on susceptibility to autoimmune and allergic diseases

31 March 2020

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Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. Mediation of specific suppression by T helper/inducer cells

31 March 2020

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Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action

31 March 2020

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Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies

31 March 2020

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Transplantation tolerance induced by antigen pretreatment and depleting anti-CD4 antibody depends on CD4+ T cell regulation during the induction phase of the response

31 March 2020

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Regulating the immune response to transplants. a role for CD4+ regulatory cells?

31 March 2020

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Identification of regulatory T cells in tolerated allografts

31 March 2020

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"Infectious" transplantation tolerance.

31 March 2020

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Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium

31 March 2020

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T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice

31 March 2020

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Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice

31 March 2020

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

31 March 2020

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Regulation of experimental allergic encephalomyelitis. Part 4. Further characterization of postrecovery suppressor cells

31 March 2020

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Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in NOD mice

31 March 2020

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Actively acquired tolerance of foreign cells

31 March 2020

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Antigen-driven bystander suppression after oral administration of antigens

31 March 2020

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Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens

31 March 2020

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Antigen-driven tissue-specific suppression following oral tolerance: orally administered myelin basic protein suppresses proteolipid protein-induced experimental autoimmune encephalomyelitis in the SJL mouse

31 March 2020

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Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

31 March 2020

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Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

31 March 2020

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Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses

31 March 2020

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Anti-CD8 Abrogates Effect of Anti-CD4–Mediated Islet Allograft Survival in Rat Model

31 March 2020

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Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

31 March 2020

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Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

31 March 2020

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The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases

31 March 2020

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Interleukin-10 and the interleukin-10 receptor

31 March 2020

1 reference

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

31 March 2020

1 reference

The activity of immunoregulatory T cells mediating active tolerance is potentiated in nonobese diabetic mice by an IL-4-based retroviral gene therapy

31 March 2020

1 reference

In vivo administration of IL-4 induces TGF-beta-producing cells and protects animals from experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Inhibitory effects of endogenous and exogenous interferon-gamma on bronchial hyperresponsiveness, allergic inflammation and T-helper 2 cytokines in Brown-Norway rats

31 March 2020

1 reference

Tolerance to islet autoantigens in type 1 diabetes

31 March 2020

1 reference

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

31 March 2020

1 reference

IL-4, IL-10, IL-13, and TGF-beta from an altered peptide ligand-specific Th2 cell clone down-regulate adoptive transfer of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

31 March 2020

1 reference

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

31 March 2020

1 reference

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

31 March 2020

1 reference

Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes

31 March 2020

1 reference

Transforming growth factor beta (TGF-beta)-dependent inhibition of T helper cell 2 (Th2)-induced autoimmunity by self-major histocompatibility complex (MHC) class II-specific, regulatory CD4(+) T cell lines.

31 March 2020

1 reference

Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering

31 March 2020

1 reference

A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance

31 March 2020

1 reference

CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses

31 March 2020

1 reference

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

31 March 2020

1 reference

CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25+ and CD25- subpopulations.

31 March 2020

1 reference

CD4+CD8- thymocytes that express L-selectin protect rats from diabetes upon adoptive transfer

31 March 2020

1 reference

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

31 March 2020

1 reference

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

31 March 2020

1 reference

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

31 March 2020

1 reference

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

31 March 2020

1 reference

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

31 March 2020

1 reference

Regulatory T cells overexpress a subset of Th2 gene transcripts

31 March 2020

1 reference

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

31 March 2020

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Induction of suppressor activity in the autologous mixed lymphocyte reaction and in cultures with concanavalin A

31 March 2020

1 reference

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

31 March 2020

1 reference

CD4+ CD25+ suppressor T cells: more questions than answers

31 March 2020

1 reference

Origin of regulatory T cells with known specificity for antigen

31 March 2020

1 reference

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

31 March 2020

1 reference

The significance of immune suppression in normal self tolerance

31 March 2020

1 reference

Peripheral autoantigen induces regulatory T cells that prevent autoimmunity

31 March 2020

1 reference

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

31 March 2020

1 reference

Both CD4(+)CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance

31 March 2020

1 reference

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.

31 March 2020

1 reference

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

31 March 2020

1 reference

Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells

31 March 2020

1 reference

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

31 March 2020

1 reference

Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse

31 March 2020

1 reference

Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4

31 March 2020

1 reference

CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes

31 March 2020

1 reference

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

31 March 2020

1 reference

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

31 March 2020

1 reference

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

31 March 2020

1 reference

Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells

31 March 2020

1 reference

T cells in murine lupus: propagation and regulation of disease

31 March 2020

1 reference

Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation

31 March 2020

1 reference

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

31 March 2020

1 reference

Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1026

1 reference

PubMed ID

12658267

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12658267