(Q33479555)

27 July 2017

title

Prediction and interaction in complex disease genetics: experience in type 1 diabetes (English)

1 reference

27 July 2017

0 references

David G Clayton

1

1 reference

27 July 2017

publication date

3 July 2009

1 reference

27 July 2017

1 reference

27 July 2017

volume

5

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27 July 2017

issue

7

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27 July 2017

page(s)

e1000540

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

3 July 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

1 reference

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Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers

21 June 2018

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Gene-gene interactions in the NOD mouse model of type 1 diabetes.

21 June 2018

1 reference

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

21 June 2018

1 reference

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Genome-based prediction of common diseases: advances and prospects

21 June 2018

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Gene-environment interactions for complex traits: definitions, methodological requirements and challenges

21 June 2018

1 reference

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Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes

21 June 2018

1 reference

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Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond

21 June 2018

1 reference

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Computational analysis of the synergy among multiple interacting genes

21 June 2018

1 reference

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A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

21 June 2018

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Confounding, ascertainment bias, and the blind quest for a genetic 'fountain of youth'.

21 June 2018

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Understanding sensitivity and specificity with the right side of the brain

21 June 2018

1 reference

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Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

21 June 2018

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Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

21 June 2018

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The language of gene interaction

21 June 2018

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A multivariate analysis of the risk of coronary heart disease in Framingham

21 June 2018

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Multiple risk factors and the prediction of coronary heart disease.

21 June 2018

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Synergy and antagonism in cause-effect relationships

21 June 2018

1 reference

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Histocompatibility (HL-A) Antigens, Lymphocytotoxic Antibodies and Tissue Antibodies in Patients with Diabetes Mellitus

21 June 2018

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Sick individuals and sick populations

21 June 2018

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Linkage strategies for genetically complex traits. I. Multilocus models

21 June 2018

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Effect modification and the limits of biological inference from epidemiologic data.

21 June 2018

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Additive, multiplicative, and other models for disease risks

21 June 2018

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The Correlation between Relatives on the Supposition of Mendelian Inheritance

21 June 2018

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A note on the background to, and refereeing of, R. A. Fisher's 1918 paper 'On the correlation between relatives on the supposition of Mendelian inheritance'.

21 January 2018

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The study of candidate genes in drug trials: sample size considerations

21 January 2018

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Epidemiology faces its limits.

21 January 2018

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PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes

21 January 2018

1 reference

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Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes

21 January 2018

1 reference

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Minimum sample size estimation to detect gene-environment interaction in case-control designs

21 January 2018

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31 October 2018

Concepts of interaction.

1 reference

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Interaction and synergism.

31 October 2018

1 reference

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Beyond odds ratios — communicating disease risk based on genetic profiles

31 October 2018

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Non-hierarchical logistic models and case-only designs for assessing susceptibility in population-based case-control studies

21 January 2018

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12 December 2020

Interaction in epidemiologic studies

1 reference

12 December 2020

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

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12 December 2020

The identification of synergism in the sufficient-component-cause framework

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12 December 2020

Association of the PTPN22/LYP gene with type 1 diabetes

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12 December 2020

Polygenic susceptibility to breast cancer and implications for prevention

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12 December 2020

10.1371/JOURNAL.PGEN.1000540

Identifiers

DOI

1 reference

release_p4rq5gdmmjhm7g5tq4gkmik22y

27 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/p4rq5gdmmjhm7g5tq4gkmik22y

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2703795

1 reference

27 July 2017

1 reference