(Q33480555)

27 July 2017

1 reference

title

Isoflavones are safe compounds for therapeutical applications - evaluation of in vitro data (English)

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27 July 2017

Alois Jungbauer

5

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author name string

Evelyne Reiter

1

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27 July 2017

Evelyne Reiter

2

1 reference

27 July 2017

Verena Beck

3

1 reference

27 July 2017

Svjetlana Medjakovic

4

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27 July 2017

publication date

1 September 2009

1 reference

Gynecological Endocrinology

27 July 2017

published in

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27 July 2017

volume

25

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27 July 2017

issue

9

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27 July 2017

page(s)

554-580

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Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from the Japan Public Health Center-based prospective study group

27 July 2017

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21 January 2018

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21 January 2018

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Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

21 January 2018

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The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast.

21 January 2018

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Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms

21 January 2018

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Comparison of hormonal activity (estrogen, androgen and progestin) of standardized plant extracts for large scale use in hormone replacement therapy

21 January 2018

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21 January 2018

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Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay

21 January 2018

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Determination of estrogenic activity in beer by biological and chemical means

21 January 2018

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Estrogenic activity of two standardized red clover extracts (Menoflavon) intended for large scale use in hormone replacement therapy

21 January 2018

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Interaction of naturally occurring nonsteroidal estrogens with expressed recombinant human estrogen receptor

21 January 2018

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Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration

21 January 2018

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Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element

21 January 2018

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Estrogenic activity of glycitein, a soy isoflavone.

21 January 2018

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Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta

21 January 2018

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https://api.crossref.org/works/10.1080%2F09513590802596461

Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer

21 January 2018

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https://api.crossref.org/works/10.1080%2F09513590802596461

Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different compounds with both receptor types.

21 January 2018

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https://api.crossref.org/works/10.1080%2F09513590802596461

High isoflavone content and estrogenic activity of 25 year-old Glycine max tissue cultures.

21 January 2018

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Phytoestrogens activate estrogen receptor beta1 and estrogenic responses in human breast and bone cancer cell lines

21 January 2018

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https://api.crossref.org/works/10.1080%2F09513590802596461

Phytoestrogens induce differential estrogen receptor alpha- or Beta-mediated responses in transfected breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F09513590802596461

Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Differential interaction of natural and synthetic estrogens with extracellular binding proteins in a yeast estrogen screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Estrogenic effects of natural and synthetic compounds including tibolone assessed in Saccharomyces cerevisiae expressing the human estrogen alpha and beta receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Cloning of a novel receptor expressed in rat prostate and ovary

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Expression of oestrogen receptor beta (ERbeta1) protein in human breast cancer biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Expression of ERalpha and ERbeta in lobular carcinoma in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Steroid hormone receptor expression in male breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Clinical significance of estrogen receptor beta in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Estrogen receptor alpha negative breast cancer patients: estrogen receptor beta as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Oestrogen receptors pathways to oestrogen responsive elements: the transactivation function-1 acts as the keystone of oestrogen receptor (ER)beta-mediated transcriptional repression of ERalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Dietary genistein increased DMBA-induced mammary adenocarcinoma in wild-type, but not ER alpha KO, mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Dual effects of phytoestrogens result in u-shaped dose-response curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Phytoestrogens inhibit aromatase but not 17beta-hydroxysteroid dehydrogenase (HSD) type 1 in human granulosa-luteal cells: evidence for FSH induction of 17beta-HSD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Inhibition of 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) activity of human lung microsomes by genistein, daidzein, coumestrol and C(18)-, C(19)- and C(21)-hydroxysteroids and ketosteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Phytoestrogens are potent inhibitors of estrogen sulfation: implications for breast cancer risk and treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein inhibits glutamate-induced apoptotic processes in primary neuronal cell cultures: an involvement of aryl hydrocarbon receptor and estrogen receptor/glycogen synthase kinase-3beta intracellular signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The hormone resistin links obesity to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The isoflavonoid aglycone-rich fractions of Chungkookjang, fermented unsalted soybeans, enhance insulin signaling and peroxisome proliferator-activated receptor-gamma activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Peroxisome proliferator-activated receptor gamma (PPARgamma ) as a molecular target for the soy phytoestrogen genistein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The balance between concurrent activation of ERs and PPARs determines daidzein-induced osteogenesis and adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein, a plant-derived isoflavone, counteracts the antilipolytic action of insulin in isolated rat adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Effects of oestrogen deprivation on interleukin-6 production by peripheral blood mononuclear cells of postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Is there a therapeutic opportunity to either prevent or treat osteopenic disorders by inhibiting marrow adipogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The Phytoestrogen Genistein Enhances Osteogenesis and Represses Adipogenic Differentiation of Human Primary Bone Marrow Stromal Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Assaying the estrogenicity of phytoestrogens in cells of different estrogen sensitive tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Mixture effects of estrogenic compounds on proliferation and pS2 expression of MCF-7 human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Molecular effects of genistein on estrogen receptor mediated pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Proliferative response of mammary glandular tissue to formononetin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Biphasic effect of daidzein on cell growth of human colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Redistribution of BRCA1 among four different protein complexes following replication blockage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Involvement of Brca2 in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Cancer susceptibility and the functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Consumption of Lactobacillus acidophilus and Bifidobacterium longum do not alter urinary equol excretion and plasma reproductive hormones in premenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Soya phytonutrients act on a panel of genes implicated with BRCA1 and BRCA2 oncosuppressors in human breast cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Apigenin suppresses cancer cell growth through ERbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Caspase-3 status is a determinant of the differential responses to genistein between MDA-MB-231 and MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Inhibition of proliferation and induction of apoptosis by genistein in colon cancer HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Preliminary studies on induction of apoptosis by genistein on HepG2 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Antiproliferative and antiangiogenic activities of genistein in human renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Effect of daidzein on cell growth, cell cycle, and telomerase activity of human cervical cancer in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Tumour angiogenesis: the relevance to surgeons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Platelet factor 4: an inhibitor of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The novel targets for anti-angiogenesis of genistein on human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Suppression of VEGF-mediated autocrine and paracrine interactions between prostate cancer cells and vascular endothelial cells by soy isoflavones

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Antiangiogenic activity of genistein in pancreatic carcinoma cells is mediated by the inhibition of hypoxia-inducible factor-1 and the down-regulation of VEGF gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Cytokines in acute and chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Initiation of acute phase response and synthesis of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Apoptosis-inducing effect of chemotherapeutic agents is potentiated by soy isoflavone genistein, a natural inhibitor of NF-kappaB in BxPC-3 pancreatic cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Interleukin 6 signal transduction in a human hepatoma cell line (Hep G2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

IL-6 production in human intestinal epithelial cells following stimulation with IL-1 beta is associated with activation of the transcription factor NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Cisplatin-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Mechanisms of the growth inhibitory effects of the isoflavonoid biochanin A on LNCaP cells and xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Inhibition of P-glycoprotein by natural products in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Soy isoflavones enhance radiotherapy in a metastatic prostate cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

The human oestrogen receptor functions in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09513590802596461

10.1080/09513590802596461

21 January 2018

Identifiers

DOI

1 reference

27 July 2017

1 reference