(Q33487093)

27 July 2017

title

Conformational heterogeneity of the M2 proton channel and a structural model for channel activation (English)

1 reference

27 July 2017

Huan-Xiang Zhou

3

0 references

author name string

Myunggi Yi

series ordinal

1

1 reference

27 July 2017

Timothy A Cross

series ordinal

2

1 reference

27 July 2017

language of work or name

English

0 references

publication date

24 July 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

27 July 2017

published in

1 reference

27 July 2017

volume

106

1 reference

27 July 2017

issue

32

1 reference

27 July 2017

page(s)

13311-13316

1 reference

Mechanism of drug inhibition and drug resistance of influenza A M2 channel

27 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

pH-induced conformational change of the influenza M2 protein C-terminal domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Spontaneous conformational change and toxin binding in alpha7 acetylcholine receptor: insight into channel activation and inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Structural basis for the function and inhibition of an influenza virus proton channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Structure and mechanism of the M2 proton channel of influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Solid-state 19F NMR spectroscopy reveals that Trp41 participates in the gating mechanism of the M2 proton channel of influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Solid-state NMR characterization of conformational plasticity within the transmembrane domain of the influenza A M2 proton channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Proton transport behavior through the influenza A M2 channel: insights from molecular simulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The chemical and dynamical influence of the anti-viral drug amantadine on the M2 proton channel transmembrane domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Histidines, heart of the hydrogen ion channel from influenza A virus: toward an understanding of conductance and proton selectivity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The M2 proton channels of influenza A and B viruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Chemical rescue of histidine selectivity filter mutants of the M2 ion channel of influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

ELEMENTARY STEPS IN ENZYME REACTIONS (AS STUDIED BY RELAXATION SPECTROMETRY).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The closed state of a H+ channel helical bundle combining precise orientational and distance restraints from solid state NMR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The open pore conformation of potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Structure of the transmembrane region of the M2 protein H+ channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Stabilizing membrane proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Protonation of histidine and histidine-tryptophan interaction in the activation of the M2 ion channel from influenza a virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Definitive assignment of proton selectivity and attoampere unitary current to the M2 ion channel protein of influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

The gating mechanism of the large mechanosensitive channel MscL

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Mechanism for proton conduction of the M(2) ion channel of influenza A virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Conformation gating as a mechanism for enzyme specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Activation of the M2 ion channel of influenza virus: a role for the transmembrane domain histidine residue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Structural characteristics of the M2 protein of influenza A viruses: evidence that it forms a tetrameric channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Influenza virus M2 protein has ion channel activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726395

Sequence determinants of a transmembrane proton channel: an inverse relationship between stability and function

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Influenza virus M2 protein: a molecular modelling study of the ion channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Gating mechanism of the influenza A M2 channel revealed by 1D and 2D IR spectroscopies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Biochemistry. Opening the molecular floodgates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Studies of structural changes in the M2 proton channel of influenza A virus by tryptophan fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Side-chain conformation of the M2 transmembrane peptide proton channel of influenza a virus from 19F solid-state NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

The influenza virus M2 ion channel protein: probing the structure of the transmembrane domain in intact cells by using engineered disulfide cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

De novo folding of membrane proteins: an exploration of the structure and NMR properties of the fd coat protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Magnitudes and Orientations of the Principal Elements of the1H Chemical Shift,1H−15N Dipolar Coupling, and15N Chemical Shift Interaction Tensors in15Nε1-Tryptophan and15Nπ-Histidine Side Chains Determined by Three-Dimensional Solid-State NMR Spec

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906553106

Differences in conductance of M2 proton channels of two influenza viruses at low and high pH

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19633188

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0906553106

1 reference

27 July 2017

0 references

1 reference

27 July 2017

1 reference