(Q36751479)

16 August 2017

Spontaneous conformational change and toxin binding in alpha7 acetylcholine receptor: insight into channel activation and inhibition (English)

1 reference

16 August 2017

Myunggi Yi

1

1 reference

16 August 2017

Harianto Tjong

series ordinal

2

1 reference

16 August 2017

Huan-Xiang Zhou

series ordinal

3

1 reference

16 August 2017

language of work or name

English

0 references

publication date

9 June 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

1 reference

16 August 2017

105

1 reference

16 August 2017

24

1 reference

16 August 2017

8280-8285

1 reference

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Backbone dynamics in an intramolecular prolylpeptide-SH3 complex from the diphtheria toxin repressor, DtxR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Electrostatic contribution to the binding stability of protein-protein complexes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Probing ion-channel pores one proton at a time

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Pore conformations and gating mechanism of a Cys-loop receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

The role of dynamics in allosteric regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Asymmetric structural motions of the homomeric alpha7 nicotinic receptor ligand binding domain revealed by molecular dynamics simulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Comparison of calculation and experiment implicates significant electrostatic contributions to the binding stability of barnase and barstar

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

SWISS-MODEL: An automated protein homology-modeling server

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

All-Atom Structure Prediction and Folding Simulations of a Stable Protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Spontaneous openings of the acetylcholine receptor channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Functional stoichiometry at the nicotinic receptor. The photon cross section for phase 1 corresponds to two bis-Q molecules per channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Arrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Agonist-induced conformational changes in the extracellular domain of alpha 7 nicotinic acetylcholine receptors

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Channel opening motion of alpha7 nicotinic acetylcholine receptor as suggested by normal mode analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Channel opening locks agonist onto the GABAC receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Electrostatic recognition and induced fit in the kappa-PVIIA toxin binding to Shaker potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

van der Waals Volumes and Radii

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Do electrostatic interactions destabilize protein-nucleic acid binding?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2448828

Molecular dynamics with coupling to an external bath

20 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Electrostatics and diffusion of molecules in solution: simulations with the University of Houston Brownian Dynamics program

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Multiple conductance states of single acetylcholine receptor channels in embryonic muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0710530105

Asymmetry of the rat acetylcholine receptor subunits in the narrow region of the pore

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18541920

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Allosteric receptors after 30 years

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18541920

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Agonist-driven conformational changes in the inner beta-sheet of alpha7 nicotinic receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18541920

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0710530105

1 reference

16 August 2017

0 references

1 reference

16 August 2017

PubMed publication ID

18541920

1 reference