(Q33501251)

27 July 2017

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title

Danaparoid. A review of its pharmacology and clinical use in the management of heparin-induced thrombocytopenia (English)

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heparin-induced thrombocytopenia

27 July 2017

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2

A Markham

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author name string

M I Wilde

series ordinal

1

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27 July 2017

A Markham

series ordinal

2

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27 July 2017

publication date

1 December 1997

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27 July 2017

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27 July 2017

volume

54

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27 July 2017

issue

6

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27 July 2017

page(s)

903-924

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Pregnancy complicated by heparin associated thrombocytopenia: management by a prospectively in vitro selected heparinoid (Org 10172).

27 July 2017

cites work

1 reference

12 December 2020

Heparin-induced thrombopenia during hemodialysis in intensive care: use of a low molecular weight heparinoid, ORG 10172 (Orgaran)

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12 December 2020

Heparin-associated thrombocytopenia: immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccharides

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12 December 2020

Influence of Chlorthalidone on the Pharmacokinetics and Pharmacodynamics of Org 10172 (Lomoparan®), A Low Molecular Weight Heparinoid, in Healthy Volunteers

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12 December 2020

Absence of in vitro cross-reaction of pentasaccharide with the plasma heparin-dependent factor of twenty-five patients with heparin-associated thrombocytopenia

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12 December 2020

Comparison of the antithrombotic effects of low molecular weight heparinoid KB-101 and heparin in a rat experimental model

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12 December 2020

Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4.

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12 December 2020

Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells

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12 December 2020

Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172)

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12 December 2020

Placental transfer of Org 10172, a low-molecular weight heparinoid, in the awake late-pregnant guinea pig.

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12 December 2020

A comparative review of the adverse effect profiles of heparins and heparinoids

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12 December 2020

Heparin-associated thrombocytopenia.

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12 December 2020

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12 December 2020

A novel anti-thrombotic heparinoid (ORG 10172) devoid of bleeding inducing capacity: A survey of its pharmacological properties in experimental animal models

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12 December 2020

Thrombosis during the use of the heparinoid Organon 10172 in a patient with heparin-induced thrombocytopenia

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12 December 2020

Interaction study between Org 10172, a low molecular weight heparinoid, and acetylsalicylic acid in healthy male volunteers

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12 December 2020

Heparin-associated thrombocytopenia type II in a patient with end-stage renal disease: successful anticoagulation with the low-molecular-weight heparinoid Org 10172 during haemodialysis.

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12 December 2020

Heparin-associated thrombocytopenia (HAT)--still a diagnostic and therapeutical problem in clinical practice

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12 December 2020

Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia.

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12 December 2020

Automated amidolytic method for determining heparin, a heparinoid, and a low-Mr heparin fragment, based on their anti-Xa activity

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12 December 2020

Danaparoid: an antithrombotic agent without major impact on triglyceride hydrolysis capacity in humans

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12 December 2020

Tolerance to intravenous administration of heparin and heparinoid in a patient with delayed-type hypersensitivity to heparins and heparinoids

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12 December 2020

Orgaran (Org 10172): its pharmacological profile in experimental models

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12 December 2020

Partial in vivo neutralisation of plasma anticoagulant effects of Lomoparan (Org 10172) by protamine chloride

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12 December 2020

In vivo activity of a new heparinoid

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12 December 2020

Pharmacology and mechanism of action of ancrod: potential for inducing thrombosis

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12 December 2020

The use of low dose Orgaran in heparin-induced thrombocytopenia associated with in vitro platelet aggregation at higher Orgaran concentrations

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12 December 2020

Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia.

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12 December 2020

Heparin induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia and thrombosis: a prospective analysis of the incidence in patients with heart and cerebrovascular diseases

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12 December 2020

Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin

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12 December 2020

Heparin-induced thrombocytopenia and antithrombotic therapy

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12 December 2020

Anticoagulant effects of a low molecular weight heparinoid (Org 10172) in human volunteers and haemodialysis patients

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12 December 2020

Heparin-associated thrombocytopenia: the antibody is not heparin specific

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12 December 2020

Antigen Generation in Heparin-Associated Thrombocytopenia: The Nonimmunologic Type and the Immunologic Type Are Closely Linked in Their Pathogenesis

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12 December 2020

The influence of Org 10172, a low molecular weight heparinoid, on antipyrine metabolism and the effect of enzyme induction on the response to Org 10172

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12 December 2020

Heparin-associated thrombocytopenia: an update

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12 December 2020

The anticoagulant effect of heparinoid Org 10172 during haemodialysis: an objective assessment

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12 December 2020

Heparin-induced platelet aggregation in anorexia nervosa and in severe peripheral vascular disease

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12 December 2020

Comparison of two experimental thrombosis models in rats effects of four glycosaminoglycans

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12 December 2020

Managing the hemorrhagic complications of heparin therapy.

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12 December 2020

A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia

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12 December 2020

Safety and pharmacokinetics of the low molecular weight heparinoid Org 10172 administered to healthy elderly volunteers

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12 December 2020

Studies of interaction of a low-molecular-weight heparinoid (Org 10172) with cloxacillin and ticarcillin in healthy male volunteers

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12 December 2020

A diagnostic test for heparin-induced thrombocytopenia

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12 December 2020

Low-Molecular-Weight Heparins and Heparinoids and their Use in Acute or Progressing Ischemic Stroke

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12 December 2020

Discordance between the anti-Xa activity and the antithrombotic activity in an ultra-low molecular weight heparin fraction

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12 December 2020

Heparin-induced thrombocytopenia and arterialthrombosis: Alternative therapies

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12 December 2020

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12 December 2020

Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thrombocytopenia.

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12 December 2020

Heparin-induced thrombocytopenia: an under-diagnosed syndrome? Proceedings of a workshop held in London on 1 November 1996

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12 December 2020

Antiplatelet drugs. A comparative review

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12 December 2020

Can low molecular weight heparins and heparinoids be safely given to patients with heparin-induced thrombocytopenia syndrome?

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12 December 2020

ORG 10172: a low molecular weight heparinoid anticoagulant with a long half-life in man.

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12 December 2020

Heparin-induced thrombocytopenia: cross-reactivity between standard heparin, low molecular weight heparin, dalteparin (Fragmin) and heparinoid, danaparoid (Orgaran).

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12 December 2020

Low-affinity material does not contribute to the antithrombotic activity of Orgaran (Org 10172) in human plasma

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12 December 2020

Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen

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12 December 2020

Interaction of ORG 10172, a low molecular weight heparinoid, and digoxin in healthy volunteers

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12 December 2020

Heparin-associated thrombocytopenia and thrombosis: a serious clinical problem and potential solution

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12 December 2020

A cross-over comparison of the anti-clotting effects of three low molecular weight heparins and glycosaminoglycuronan

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12 December 2020

Thrombosis and the pharmacology of antithrombotic agents

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12 December 2020

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12 December 2020

Thrombosis prophylaxis in an AT III deficient pregnant woman: application of a low molecular weight heparinoid

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12 December 2020

Heparin-associated thrombosis despite normal platelet counts

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12 December 2020

Heparin-induced thrombocytopenia: laboratory studies

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12 December 2020

Time courses of the antithrombotic effects, bleeding enhancing effects and interactions with factors Xa and thrombin after administration of low molecular weight heparinoid Org 10172 or heparin to rats

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12 December 2020

Platelet aggregation in response to four low molecular weight heparins and the heparinoid ORG 10172 in patients with heparin-induced thrombocytopenia

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12 December 2020

Heparin-associated thrombocytopenia: a critical review and pooled analysis.

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12 December 2020

Anticoagulant mechanisms of Orgaran (Org 10172) and its fraction with high affinity to antithrombin III (Org 10849)

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12 December 2020

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12 December 2020

A 14-year study of heparin-induced thrombocytopenia

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12 December 2020

Heparin-associated thrombocytopenia: successful therapy of patients after prospective selection of a compatible heparinoid with the heparin-induced platelet activation test

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12 December 2020

Delayed cutaneous reaction to unfractionated heparin, low molecular weight heparin and danaparoid

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12 December 2020

Heparin as a cause of thrombus progression. Heparin-associated thrombocytopenia is an important differential diagnosis in paediatric patients even with normal platelet counts

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12 December 2020

Thrombocytopenia in a prospective, randomized, double-blind trial of bovine and porcine heparin

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12 December 2020

Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia

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12 December 2020

Treatment of heparin-induced thrombocytopenia and thrombosis.

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12 December 2020

[Value of orgaran in hemodialysis during heparin-induced thrombopenia]

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12 December 2020

Platelet activation following intravenous injection of a conventional heparin: absence of effect with a low molecular weight heparinoid (Org 10172).

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12 December 2020

Coagulation disorders in cancer

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12 December 2020

Novel Antithrombotic Drugs in Development

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12 December 2020

Pharmacokinetic considerations on Orgaran (Org 10172) therapy

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12 December 2020

A new low molecular weight heparinoid Org 10172 as anticoagulant in hemodialysis.

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12 December 2020

Comparison of the effect of a conventional heparin and a low molecular weight heparinoid on platelet function

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12 December 2020

Cross-reactivity study of low molecular weight heparins and heparinoid in heparin-induced thrombocytopenia

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12 December 2020

The use of a low molecular weight heparinoid (Org 10172) for extracorporeal procedures in patients with heparin dependent thrombocytopenia and thrombosis

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12 December 2020

Large-dose infusions of heparinoid ORG 10172 in ischemic stroke.

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12 December 2020

10.2165/00003495-199754060-00008

Identifiers

DOI

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Dimensions Publication ID

27 July 2017

1031242180

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