(Q33508967)

27 July 2017

title

A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity (English)

1 reference

27 July 2017

Rodrigo Barderas

2

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author name string

Peter Timmerman

1

1 reference

27 July 2017

Johan Desmet

3

1 reference

27 July 2017

Danièle Altschuh

4

1 reference

27 July 2017

Susana Shochat

5

1 reference

27 July 2017

Martine J Hollestelle

6

1 reference

27 July 2017

Jo W M Höppener

7

1 reference

27 July 2017

Alberto Monasterio

8

1 reference

27 July 2017

J Ignacio Casal

9

1 reference

27 July 2017

Rob H Meloen

10

1 reference

27 July 2017

language of work or name

English

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publication date

6 October 2009

1 reference

Journal of Biological Chemistry

27 July 2017

published in

1 reference

27 July 2017

volume

284

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27 July 2017

issue

49

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27 July 2017

page(s)

34126-34134

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Gastrin is an essential cofactor for helicobacter-associated gastric corpus carcinogenesis in C57BL/6 mice

27 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Affinity maturation of antibodies assisted by in silico modeling.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Designing antibodies for the inhibition of gastrin activity in tumoral cell lines.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Ranibizumab for the treatment of neovascular age-related macular degeneration: a review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

A fast mutagenesis procedure to recover soluble and functional scFvs containing amber stop codons from synthetic and semisynthetic antibody libraries

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Potent antibody therapeutics by design

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Engineered antibody fragments and the rise of single domains

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Analysis of a 17-amino acid residue, virus-neutralizing microantibody.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Nanobodies as novel agents for cancer therapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits binding of vascular endothelial growth factor to its receptor.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Rapid tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130Cas by gastrin in human colon cancer cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Phase II study of anti-gastrin-17 antibodies, raised to G17DT, in advanced pancreatic cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Intramers as promising new tools in functional proteomics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Plastic antibodies: developments and applications.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Anatomy of an antibody molecule: structure, kinetics, thermodynamics and mutational studies of the antilysozyme antibody D1.3.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Therapeutic peptides and peptidomimetics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Gastrin gene expression is required for the proliferation and tumorigenicity of human colon cancer cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Identification of gastrin as a growth peptide in human pancreatic cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

Characterization of a new primary human pancreatic tumor line.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797183

A phase II study of G17DT in gastric carcinoma

14 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041459

Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041459

Mapping of a discontinuous and highly conformational binding site on follicle stimulating hormone subunit-beta (FSH-beta) using domain Scan and Matrix Scan technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041459

Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041459

Synthetic CD4 exocyclic peptides antagonize CD4 holoreceptor binding and T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041459

Monoclonal antibody successes in the clinic

21 January 2018

1 reference

12 December 2020

Monoclonal antibody therapy of cancer

1 reference

12 December 2020

Expression of gastrin and its receptor in human gastric cancer tissues

1 reference

12 December 2020

G17DT: an antigastrin immunogen for the treatment of gastrointestinal malignancy

1 reference

12 December 2020

Small antibody mimetics comprising two complementarity-determining regions and a framework region for tumor targeting

1 reference

12 December 2020

Battle over eye medicine gives drugmaker a dose of reality

1 reference

12 December 2020

A peptide mimetic of an anti-CD4 monoclonal antibody by rational design

1 reference

12 December 2020

Role of gastrin and gastrin receptors on the growth of a transplantable mouse colon carcinoma (MC-26) in BALB/c mice

1 reference

12 December 2020

Growth-promoting action of gastrin on human colonic and gastric tumour cells cultured in vitro

1 reference

12 December 2020

Inhibition of Self-Binding Antibodies (Autobodies) by a V H -Derived Peptide

1 reference

12 December 2020

Antibody framework residues affecting the conformation of the hypervariable loops

1 reference

12 December 2020

Gastrin regulates growth of human pancreatic cancer in a tonic and autocrine fashion

1 reference

12 December 2020

Dissection of an antibody paratope into peptides discloses the idiotope recognized by the cognate anti-idiotypic antibody

1 reference

12 December 2020

A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing

1 reference

12 December 2020

Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNF alpha binding to its receptor

1 reference

12 December 2020

Systematic exploration of the antigen binding activity of synthetic peptides isolated from the variable regions of immunoglobulins

1 reference

12 December 2020

Rapid and quantitative cyclization of multiple peptide loops onto synthetic scaffolds for structural mimicry of protein surfaces

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.041459

1 reference

27 July 2017

1 reference

27 July 2017

1 reference