(Q33518250)

27 July 2017

title

Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies (English)

1 reference

27 July 2017

0 references

1 reference

Yong-Sung Kim

5

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author name string

Woo-Ram Lee

1

1 reference

27 July 2017

Ji-Young Jang

2

1 reference

27 July 2017

Jeong-Sun Kim

3

1 reference

27 July 2017

Myung-Hee Kwon

4

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27 July 2017

language of work or name

English

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publication date

9 December 2009

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27 July 2017

published in

Nucleic Acids Research

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27 July 2017

volume

38

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27 July 2017

issue

5

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27 July 2017

page(s)

1596-1609

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A novel agonistic antibody to human death receptor 4 induces apoptotic cell death in various tumor cells without cytotoxicity in hepatocytes

27 July 2017

cites work

1 reference

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Normalization of qRT-PCR data: the necessity of adopting a systematic, experimental conditions-specific, validation of references

21 June 2018

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Origins and Mechanisms of miRNAs and siRNAs

21 June 2018

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Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling

21 June 2018

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A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L

21 June 2018

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Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Synthetic antibodies for specific recognition and crystallization of structured RNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Recombinant immunoproapoptotic proteins with furin site can translocate and kill HER2-positive cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Creating a ribonuclease T-tat that preferentially recognizes and hydrolyzes HIV-1 TAR RNA in vitro and in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Structural modeling of sequence specificity by an autoantibody against single-stranded DNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Illuminating the silence: understanding the structure and function of small RNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Protein i: interference at protein level by intrabodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Sequence-specific binding of single-stranded RNA: is there a code for recognition?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Enhancing and confirming the specificity of RNAi experiments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Construction and characterization of a pseudo-immune human antibody library using yeast surface display

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Destroying RNA as a therapeutic approach

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Nuclear localizing anti-DNA antibodies enter cells via caveoli and modulate expression of caveolin and p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

TransMabs: cell-penetrating antibodies, the next generation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Approaches for the sequence-specific knockdown of mRNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Antibody penetration into living cells: pathogenic, preventive and immuno-therapeutic implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Cytotoxic ribonucleases: molecular weapons and their targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Generation of sequence-specific, high affinity anti-DNA antibodies.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Polyreactive anti-DNA monoclonal antibodies and a derived peptide as vectors for the intracytoplasmic and intranuclear translocation of macromolecules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

RNA base-amino acid interaction strengths derived from structures and sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

Fusion with an RNA binding domain to confer target RNA specificity to an RNase: design and engineering of Tat-RNase H that specifically recognizes and cleaves HIV-1 RNA in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836572

A nucleic acid-hydrolyzing antibody penetrates into cells via caveolae-mediated endocytosis, localizes in the cytosol and exhibits cytotoxicity

21 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKP1145

Generation of humanized anti-DNA hydrolyzing catalytic antibodies by complementarity determining region grafting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKP1145

A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKP1145

A Comprehensive Model for the Cellular Uptake of Cationic Cell-penetrating Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKP1145

Anti-DNA autoantibodies reveal toxicity to tumor cell lines

21 January 2018

1 reference

12 December 2020

Ribonuclease inhibitor from human placenta. Purification and properties

1 reference

12 December 2020

Mechanisms of cellular penetration and nuclear localization of an anti-double strand DNA autoantibody

1 reference

12 December 2020

Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: potential advantages over antibodies expressed within the intracellular environment (Intrabody)

1 reference

12 December 2020

Cell-penetrating anti-native DNA antibodies trigger apoptosis through both the neglect and programmed pathways

1 reference

12 December 2020

Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity

1 reference

12 December 2020

DNA and heparin alter the internalization process of anti-DNA monoclonal antibodies according to patterns typical of both the charged molecule and the antibody

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKP1145

1 reference

27 July 2017

1 reference

27 July 2017

1 reference