(Q33522211)

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Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene.

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scholarly article

1 reference

Europe PubMed Central

27 July 2017

Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene. (English)

1 reference

Europe PubMed Central

27 July 2017

author name string

Lynda Li Song

1

1 reference

Europe PubMed Central

27 July 2017

Larissa Ponomareva

2

1 reference

Europe PubMed Central

27 July 2017

Hui Shen

3

1 reference

Europe PubMed Central

27 July 2017

Xin Duan

4

1 reference

Europe PubMed Central

27 July 2017

Fatouma Alimirah

5

1 reference

Europe PubMed Central

27 July 2017

Divaker Choubey

6

1 reference

Europe PubMed Central

27 July 2017

language of work or name

0 references

publication date

5 January 2010

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

5

1 reference

Europe PubMed Central

27 July 2017

1

1 reference

Europe PubMed Central

27 July 2017

e8569

1 reference

Europe PubMed Central

27 July 2017

copyright license

Creative Commons CC0 License

5 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

IFI16 and NM23 bind to a common DNA fragment both in the P53 and the cMYC gene promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Expression of an IFN-inducible cellular senescence gene, IFI16, is up-regulated by p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Myc's broad reach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Interferon-inducible Ifi200-family genes in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Actions of human telomerase beyond telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Interferons at age 50: past, current and future impact on biomedicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Interferon-inducible IFI16 protein in human cancers and autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

How cells respond to interferons revisited: from early history to current complexity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Type I interferon prolongs cell cycle progression via p21WAF1/CIP1 induction in human colon cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

IFI16 inhibits tumorigenicity and cell proliferation of bone and cartilage tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Telomere dysfunction as a cause of genomic instability in Werner syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

AlphaCP1 mediates stabilization of hTERT mRNA by autocrine human growth hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Complex modulation of cell type-specific signaling in response to type I interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Type 1 interferons and the virus-host relationship: a lesson in détente .

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: implications for the androgen receptor functions and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Telomere and telomerase dynamics in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Small-molecule-based identification of dynamic assembly of E2F-pocket protein-histone deacetylase complex for telomerase regulation in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Role of IFI 16 in cellular senescence of human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Autorepression of c-myc requires both initiator and E2F-binding site elements and cooperation with the p107 gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Multiple tumor suppressor pathways negatively regulate telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Interferon-inducible p202 in the susceptibility to systemic lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

P202: an interferon-inducible negative regulator of cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Second-generation interferons for cancer: clinical targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Novel functions of interferon-induced proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

The interferon- and differentiation-inducible p202a protein inhibits the transcriptional activity of c-Myc by blocking its association with Max.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Creation of human tumour cells with defined genetic elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Telomerase activity in myeloma cells is closely related to cell cycle status, but not to apoptotic signals induced by interferon-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Myc activates telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Inhibition of E2F-4/DP-1-stimulated transcription by p202.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Inhibition of E2F-mediated transcription by p202

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Regulation of telomerase activity in immortal cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Binding of an interferon-inducible protein (p202) to the retinoblastoma protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Differential regulation of interferon-induced mRNAs and c-myc mRNA by alpha- and gamma-interferons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

21 June 2018

Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Telomere dysfunction increases mutation rate and genomic instability

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Telomerase regulation at the telomere: a binary switch.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Telomerase maintains telomere structure in normal human cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Different effects of interferon-alpha on melanoma cell lines: a study on telomerase reverse transcriptase, telomerase activity and apoptosis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Interferon regulatory factor-1 (IRF-1) is a mediator for interferon-gamma induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Close link between reduction of c-myc expression by interferon and, G0/G1 arrest

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Interferon-alpha repressed telomerase along with G1-accumulation of Daudi cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Cell cycle dependent telomere regulation by telomerase in human bone marrow mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0008569

21 January 2018

Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: a promising implication of telomerase-dependent targeted cancer gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

31 October 2018

Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797294

31 October 2018

Interferon alpha down-regulates telomerase reverse transcriptase and telomerase activity in human malignant and nonmalignant hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20052289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20052289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synchronization of human diploid fibroblasts at multiple stages of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20052289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20052289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0008569

1 reference

Europe PubMed Central

27 July 2017

2010PLoSO...5.8569S

0 references

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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