(Q33912829)

30 July 2017

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title

Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology (English)

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30 July 2017

1

Wright WE

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30 July 2017

Shay JW

2

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30 July 2017

language of work or name

English

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publication date

1 August 2000

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

8

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30 July 2017

page(s)

849-851

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https://scigraph.springernature.com/pub.10.1038/78592

30 July 2017

exact match

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cites work

The serial cultivation of human diploid cell strains

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7 January 2021

The two-stage mechanism controlling cellular senescence and immortalization

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7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

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7 January 2021

A role for both RB and p53 in the regulation of human cellular senescence

1 reference

7 January 2021

Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

1 reference

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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7 January 2021

Telomerase activity is sufficient to allow transformed cells to escape from crisis

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7 January 2021

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

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7 January 2021

Tumor surveillance via the ARF-p53 pathway.

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7 January 2021

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

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7 January 2021

Cell aging in vivo and in vitro

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7 January 2021

Extended culture of mouse embryo cells without senescence: inhibition by serum.

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7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

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7 January 2021

Dual roles of ATM in the cellular response to radiation and in cell growth control.

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7 January 2021

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

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7 January 2021

Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

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7 January 2021

The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome

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7 January 2021

For better or worse? Telomerase inhibition and cancer

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7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

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7 January 2021

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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7 January 2021

Regulation of telomerase activity in immortal cell lines

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7 January 2021

Identifiers

DOI

10.1038/78592

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Dimensions Publication ID

30 July 2017

1032345919

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